Erythrocyte, platelet, serum ferritin, and P-selectin pathophysiology implicated in severe hypercoagulation and vascular complications in COVID-19

C Venter, JA Bezuidenhout, GJ Laubscher… - International journal of …, 2020 - mdpi.com
Progressive respiratory failure is seen as a major cause of death in severe acute respiratory
syndrome coronavirus 2 (SARS-Cov-2)-induced infection. Relatively little is known about the …

Altered platelet and coagulation function in moderate-to-severe COVID-19

RI Litvinov, NG Evtugina, AD Peshkova, SI Safiullina… - Scientific reports, 2021 - nature.com
To reveal if coagulopathies relate to the course of COVID-19, we examined 255 patients with
moderate and severe COVID-19, receiving anticoagulants and immunosuppressive drugs …

Prothrombotic phenotype in COVID-19: focus on platelets

C Barale, E Melchionda, A Morotti, I Russo - International Journal of …, 2021 - mdpi.com
COVID-19 infection is associated with a broad spectrum of presentations, but alveolar
capillary microthrombi have been described as a common finding in COVID-19 patients …

Microvascular thrombosis as a critical factor in severe COVID-19

PP Wadowski, B Panzer, A Józkowicz… - International Journal of …, 2023 - mdpi.com
Platelet–endothelial interactions have a critical role in microcirculatory function, which
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …

Modulation of hemostasis in COVID-19; blood platelets may be important pieces in the COVID-19 puzzle

M Ulanowska, B Olas - Pathogens, 2021 - mdpi.com
Although the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently
remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease …

Upregulation of cytokine signalling in platelets increases risk of thrombophilia in severe COVID-19 patients

S Kaur, A Singh, J Kaur, N Verma, AK Pandey… - Blood Cells, Molecules …, 2022 - Elsevier
Abnormal coagulation dynamics, including disseminated intravascular coagulopathy,
pulmonary embolism, venous thromboembolism and risk of thrombosis are often associated …

[HTML][HTML] Coagulation disorders and thrombosis in COVID-19 patients and a possible mechanism involving endothelial cells: a review

A Chen, C Wang, W Zhu, W Chen - Aging and Disease, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is still an ongoing pandemic worldwide.
COVID-19 is an age-related disease with a higher risk of organ dysfunction and mortality in …

The role of platelets, neutrophils and endothelium in COVID-19 infection

E Falcinelli, E Petito, P Gresele - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction COVID-19 is associated to an increased risk of thrombosis, as a result of a
complex process that involves the activation of vascular and circulating cells, the release of …

The impact of COVID-19 disease on platelets and coagulation

GD Wool, JL Miller - Pathobiology, 2021 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some
patients develop a severe proinflammatory state which can be associated with a unique …

Platelets promote thromboinflammation in SARS-CoV-2 pneumonia

F Taus, G Salvagno, S Canè, C Fava… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Pulmonary thrombosis is observed in severe acute respiratory syndrome
coronavirus 2 pneumonia. Aim was to investigate whether subpopulations of platelets were …