Human cytomegalovirus cell tropism and pathogenesis

C Sinzger, G Jahn - Intervirology, 1996 - karger.com
The human cytomegalovirus (HCMV) can cause lifelong infection with episodes of
endogenous reactivation. Intrauterine fetal infection and infection of immunocompromised …

Cytomegalovirus cell tropism

C Sinzger, M Digel, G Jahn - Human cytomegalovirus, 2008 - Springer
The human cytomegalovirus (HCMV) can infect a remarkably broad cell range within its
host, including parenchymal cells and connective tissue cells of virtually any organ and …

The pathogenesis of human cytomegalovirus

P Griffiths, I Baraniak, M Reeves - The Journal of pathology, 2015 - Wiley Online Library
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft
recipient and AIDS patients. More recently, it has been recognized as a pathogen for those …

Cytomegalovirus persistence in macrophages and endothelial cells.

KN Fish, SG Stenglein, C Ibanez… - Scandinavian journal of …, 1995 - europepmc.org
Although human cytomegalovirus (HCMV) rarely causes overt disease in healthy
individuals, the virus can be a serious, even life-threatening problem in immunosuppressed …

Human cytomegalovirus induces monocyte differentiation and migration as a strategy for dissemination and persistence

MS Smith, GL Bentz, JS Alexander… - Journal of virology, 2004 - Am Soc Microbiol
Human cytomegalovirus (HCMV) pathogenesis is characterized by multiple organ system
involvement due to viral spread to host organs after a cell-associated viremia. The cell type …

Overview of human cytomegalovirus pathogenesis

HL Fulkerson, MT Nogalski, D Collins-McMillen… - … : Methods and Protocols, 2021 - Springer
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60–
90%. HCMV is the leading cause of congenital infections and poses a great health risk to …

Cell types involved in replication and distribution of human cytomegalovirus

B Plachter, C Sinzger, G Jahn - Advances in virus research, 1996 - Elsevier
Publisher Summary This chapter discusses the interaction of human cytomegalovirus
(HCMV) with different host cells in vitro and in vivo. The role of different cell populations in …

Tissue macrophages are infected by human cytomegalovirus in vivo

C Sinzger, B Plachter, A Grefte, TH The… - The Journal of …, 1996 - academic.oup.com
On the basis of in vitro experiments, it has been suggested that cells of hematopoietic origin
play a major role in the pathogenesis and latency of human cytomegalovirus (HCMV). To …

Human cytomegalovirus productively infects primary differentiated macrophages

CE Ibanez, R Schrier, P Ghazal, C Wiley… - Journal of …, 1991 - Am Soc Microbiol
Monocytes are one of the predominant cell types in the peripheral blood that are infected by
human cytomegalovirus (HCMV). Although virus can be detected in these cells in vivo …

Overview of human cytomegalovirus pathogenesis

MT Nogalski, D Collins-McMillen… - … : methods and protocols, 2014 - Springer
Human cytomegalovirus (HCMV) is a human pathogen that infects greater than 50% of the
human population. HCMV infection is usually asymptomatic in most individuals. That is …