Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor
DJ Glass, SH Nye, P Hantzopoulos, MJ Macchi… - Cell, 1991 - cell.com
The neurotrophins(nerve growth factor [NGF], brainderived neurotrophic factor [BDNF],
neurotrophin-3 [NT-31, and neurotrophin-4 [NT-41) have been defined by their ability to …
neurotrophin-3 [NT-31, and neurotrophin-4 [NT-41) have been defined by their ability to …
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
SP Squinto, TN Stitt, TH Aldrich, S Davis, SM Blanco… - Cell, 1991 - cell.com
A variety of findings seem to functionally link brainderived neurotrophic factor (BDNF))'and
neurotrophin3 (NT-3), while distinguishing both of these factors from the third member of the …
neurotrophin3 (NT-3), while distinguishing both of these factors from the third member of the …
Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses
L Minichiello, F Casagranda, RS Tatche, CL Stucky… - Neuron, 1998 - cell.com
Neurotrophins are a family of soluble ligands that promote the survival and differentiation of
peripheral and central neurons and regulate synaptic function. The two neurotrophins, brain …
peripheral and central neurons and regulate synaptic function. The two neurotrophins, brain …
Binding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by TrkC (∗)
M Rydén, CF Ibánez - Journal of Biological Chemistry, 1996 - ASBMB
Neurotrophins regulate differentiation and survival of vertebrate neurons through binding to
members of the Trk family of receptor tyrosine kinases and to a common low affinity receptor …
members of the Trk family of receptor tyrosine kinases and to a common low affinity receptor …
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
P Tsoulfas, D Soppet, E Escandon, L Tessarollo… - Neuron, 1993 - cell.com
Members of the Trk tyrosine kinase family have recently been identified as functional
receptors of the NGF family of neurotrophins. Here we show the rat trkC locus to be complex …
receptors of the NGF family of neurotrophins. Here we show the rat trkC locus to be complex …
[HTML][HTML] Early evolutionary origin of the neurotrophin receptor family
RE van Kesteren, M Fainzilber, G Hauser… - The EMBO …, 1998 - embopress.org
Neurotrophins and their Trk receptors play a crucial role in the development and
maintenance of the vertebrate nervous system, but to date no component of this signalling …
maintenance of the vertebrate nervous system, but to date no component of this signalling …
Structural and functional properties of the TRK family of neurotrophin receptors.
M Barbacid - Annals of the new York Academy of Sciences, 1995 - europepmc.org
The Trk family of tyrosine-protein kinases, TrkA, TrkB, and TrkC, are the signaling receptors
that mediate the biological properties of the NGF family of neurotrophins. This family of …
that mediate the biological properties of the NGF family of neurotrophins. This family of …
Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling
FF Eide, ER Vining, BL Eide, K Zang… - Journal of …, 1996 - Soc Neuroscience
trkB encodes a receptor tyrosine kinase activated by three neurotrophins—brain-derived
neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4/5. In vivo, three isoforms of …
neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4/5. In vivo, three isoforms of …
Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells
We have exploited a battery of approaches to address several controversies that have
accompanied the expansion of the nerve growth factor (NCF) family of neurotrophic factors …
accompanied the expansion of the nerve growth factor (NCF) family of neurotrophic factors …
Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture
HN Marsh, WK Scholz, F Lamballe, R Klein… - Journal of …, 1993 - Soc Neuroscience
The trkB gene encodes a tyrosine kinase receptor, gp145trkB, for brain-derived neurotrophic
factor (BDNF) and neurotrophin-4 (NT-4). To understand the role of gp145trkB in the …
factor (BDNF) and neurotrophin-4 (NT-4). To understand the role of gp145trkB in the …