Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

[HTML][HTML] Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

SB Anderberg, T Luther, M Berglund, R Larsson… - Cytokine, 2021 - Elsevier
Background The infection caused by SARS CoV-2 has been postulated to induce a cytokine
storm syndrome that results in organ failure and even death in a considerable number of …

[HTML][HTML] Plasma IL-6 levels following corticosteroid therapy as an indicator of ICU length of stay in critically ill COVID-19 patients

S Awasthi, T Wagner, AJ Venkatakrishnan… - Cell death …, 2021 - nature.com
Intensive care unit (ICU) admissions and mortality in severe COVID-19 patients are driven
by “cytokine storms” and acute respiratory distress syndrome (ARDS). Interim clinical trial …

The Management of Cytokine Storm in COVID-19.

CM Rumende, EC Susanto, TP Sitorus - Acta Medica Indonesiana, 2020 - europepmc.org
Cytokine storm in COVID-19 infection is an excessive immune response to external stimuli
where the pathogenesis is complex. The disease progresses rapidly and the mortality is …

[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
Dear Editor, Coronavirus disease 2019 (COVID-19) is an infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) with the symptoms …

Dysregulated host response in severe acute respiratory syndrome coronavirus 2-induced critical illness

S Tiwari-Heckler, C Rauber, MS Longhi… - Open Forum …, 2021 - academic.oup.com
Background Impaired immune response has been reported to be the cause of the
development of coronavirus disease 2019 (COVID-19)-related respiratory failure. Further …

[HTML][HTML] Consideration of severe coronavirus disease 2019 as viral sepsis and potential use of immune checkpoint inhibitors

Z Odabasi, I Cinel - Critical care explorations, 2020 - journals.lww.com
Taking into consideration the multisystemic clinical and autopsy findings in “severe”
coronavirus disease 2019 patients, viral sepsis would be a more accurate term to describe …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
Clinical intervention in patients with corona virus disease 2019 (COVID-19) has
demonstrated a strong upregulation of cytokine production in patients who are critically ill …

[HTML][HTML] Cytokine storm in novel coronavirus disease (COVID-19): expert management considerations

Y Mehta, SB Dixit, KG Zirpe… - Indian journal of critical …, 2020 - ncbi.nlm.nih.gov
Background Cytokine storm is caused by the colossal release of proinflammatory cytokines
[eg, IL (interleukin)-2, IL-6, IL-8 TNF (tumor necrosis factor)-α, etc.] causing dysregulated …