Although epidemiological studies provide strong support for demographic and
environmental risk factors in psychotic disorders, few data examine how these risk factors …

Background Psychiatric disorders are highly heritable and polygenic, and many have their
peak onset in late childhood and adolescence, a period of tremendous changes. Although …

Childhood maltreatment (abuse or neglect) can result in changes to the brain structures and
functions that underlie adult depression. Few studies have explored the impact of childhood …

The restructuring and optimization of the cerebral cortex from early childhood and through
adolescence is an essential feature of human brain development, underlying immense …

This study aimed to identify white-matter microstructural characteristics associated with risk
for pediatric major depressive disorder (MDD) measured by the Child Behavior Checklist …

While white matter structural integrity is likely to influence the responses to social-emotional
stimuli and emotional regulation during development, no longitudinal data are available on …

Abstract Background Diffusion Tensor Imaging (DTI) studies of traumatic brain injury (TBI)
have focused on alterations in microstructural features of deep white matter fibers (DWM) …

Adolescence is a period of major brain reorganization shaped by biologically timed and by
environmental factors. We sought to discover linked patterns of covariation between brain …

Previous studies have found developmental differences between males and females in
brain structure. During childhood and adolescence, relative white matter volume increases …

Previous studies have suggested that amnestic mild cognitive impairment (aMCI) is
associated with changes in cortical morphological features, such as cortical thickness, sulcal …