The development of mathematical models capable of predicting the lifespan of animals is
growing. However, there are no studies that compare the predictive power of different sets of …

The identification of predictive markers of life span would help to unravel the underlying
mechanisms influencing ageing and longevity. For this aim, 30 variables including immune …

Chronological age is not a good indicator of how each individual ages and thus how to
maintain good health. Due to the long lifespan in humans and the consequent difficulty of …

Immune function and redox markers are used for estimating the aging rate, namely
biological age (BA). However, it is unknown if this BA and its changes can be reflected in …

Aging is a heterogeneous process, so individuals of the same age may be aging at a
different rate. A natural model of premature aging in mice have been proposed based on the …

Finding biomarkers to assess the rate of ageing and consequently, to forecast individual
lifespan is a challenge in ageing research. We recently published a mathematical model for …

The aging process is a universal, intrinsic, progressive accumulation of deleterious changes
in cells and tissues that increases morbidity and leads to death. The heterogeneity of the …

Oxidative stress has been reported to increase with aging, and although several age-related
changes in redox parameters have been described, none of them have been verified as …

Since the late 18th century, the murine model has been widely used in biomedical research
(about 59% of total animals used) as it is compact, cost-effective, and easily available …

The intensity of behavioral and neuroendocrine responses to stressful stimuli in rodent
strains seems to be inversely related to their life span. We have previously shown that …