GFP-like fluorescent proteins and their molecular mimics have revolutionized bioimaging
research, but their emissions are largely limited in the visible to far-red region, hampering …

Red fluorescent proteins (RFPs) have emerged as valuable biological markers for
biomolecule imaging in living systems. Developing artificial fluorogenic systems that mimic …

RNA viruses represent a major global health threat, and the visualization of their RNA
genome in infected cells is essential for virological research and clinical diagnosis. Due to …

We have demonstrated that the subcellular targeting properties of the indole-based
cyanines can be tuned by the functional substituent attached onto the indole moiety in which …

Fluorogenic hybridization probes that allow RNA imaging provide information as to how the
synthesis and transport of particular RNA molecules is orchestrated in living cells. In this …

In light of the increasing importance assigned to RNA, significant efforts have been devoted
to the development of fluorescent oligonucleotide probes that allow the imaging of RNA …

Green fluorescence proteins (GFP) are appealing to a variety of biomedical and
biotechnology applications, such as protein fusion, subcellular localizations, cell …

Highlights•Synthetic analogs of GFP chromophores are new classes of fluorogens.•Their
fluorescence increases 10–1000 folds upon binding to specific host molecules.•Hosts range …

We strategically modified the GFP core via chemical synthesis to make redder and brighter
biomimetic fluorophores. Based on quantum calculations, solvatochromism analysis, and …

Fluorescence bioimaging has recently jumped into a new area of spatiotemporal resolution
and sensitivity thanks to synergistic advances in both optical physics and probe/biosensor …