The immunopathological and histological landscape of COVID-19-mediated lung injury

G Zarrilli, V Angerilli, G Businello, M Sbaraglia… - International Journal of …, 2021 - mdpi.com
A complete understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) physiopathology and related histopathologic lesions is necessary to improve treatment …

Back to basics in COVID‐19: antigens and antibodies—completing the puzzle

M Neagu, D Calina, AO Docea… - Journal of Cellular …, 2021 - Wiley Online Library
The outbreak of the coronavirus disease 2019 (COVID‐19) has gathered 1 year of
scientific/clinical information. This informational asset should be thoroughly and wisely used …

[HTML][HTML] Immunomodulation for severe COVID-19 pneumonia: the state of the art

Y Zhang, Y Chen, Z Meng - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has become a worldwide pandemic caused by the novel coronavirus named
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe cases of COVID-19 …

[HTML][HTML] A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

SB Polak, IC Van Gool, D Cohen, JH von der Thüsen… - Modern Pathology, 2020 - Elsevier
Since the outbreak of the COVID-19 pandemic, much has been learned regarding its clinical
course, prognostic inflammatory markers, disease complications, and mechanical ventilation …

Monocytes and macrophages, targets of severe acute respiratory syndrome coronavirus 2: the clue for coronavirus disease 2019 immunoparalysis

A Boumaza, L Gay, S Mezouar, E Bestion… - The Journal of …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) clinical expression is
pleiomorphic, severity is related to age and comorbidities such as diabetes and …

Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …

M Sokolowska, ZM Lukasik, I Agache, CA Akdis… - Allergy, 2020 - Wiley Online Library
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …

[HTML][HTML] COVID-19: unravelling the clinical progression of nature's virtually perfect biological weapon

G Lippi, F Sanchis-Gomar, BM Henry - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) pandemic has shocked the world and
caused morbidity and mortality on an unprecedented level in the era of modern medicine …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
The exaggerated immune response induced in the lower respiratory tract against
coronaviruses (CoVs), including CoViD-19 (2019-nCoV), appears to contribute to the …

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

NAF Janssen, I Grondman… - The Journal of …, 2021 - academic.oup.com
The clinical spectrum of COVID-19 varies and the differences in host response
characterizing this variation have not been fully elucidated. COVID-19 disease severity …