The immune system and COVID-19: Friend or foe?

F Yazdanpanah, MR Hamblin, N Rezaei - Life sciences, 2020 - Elsevier
Abstract Aim Coronavirus disease 2019 (COVID-19) is a novel highly contagious infection
caused by SARS-CoV-2, which has been became a global public health challenge. The …

[HTML][HTML] Immune alterations in a patient with SARS-CoV-2-related acute respiratory distress syndrome

L Bouadma, A Wiedemann, J Patrier… - Journal of clinical …, 2020 - Springer
We report a longitudinal analysis of the immune response associated with a fatal case of
COVID-19 in Europe. This patient exhibited a rapid evolution towards multiorgan failure …

[HTML][HTML] Cell-mediated immune responses to COVID-19 infection

A Guihot, E Litvinova, B Autran, P Debre… - Frontiers in …, 2020 - frontiersin.org
An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV),
subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

[HTML][HTML] Immunologic features in coronavirus disease 2019: functional exhaustion of T cells and cytokine storm

S Mahmoudi, M Rezaei, N Mansouri, M Marjani… - Journal of clinical …, 2020 - Springer
To the Editor: Since the emergence of Coronavirus Disease 2019 (COVID-19) caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in December 2019, the …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

[HTML][HTML] Parallels in sepsis and COVID-19 conditions: implications for managing severe COVID-19

CO Olwal, NN Nganyewo, K Tapela… - Frontiers in …, 2021 - frontiersin.org
Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to
infection. Sepsis is a global burden killing~ 11 million persons annually. In December 2019 …

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

DS Battagello, G Dragunas, MO Klein… - Clinical …, 2020 - portlandpress.com
The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of
coronaviruses–the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[PDF][PDF] Heightened innate immune responses in the respiratory tract of COVID-19 patients

Z Zhou, L Ren, L Zhang, J Zhong, Y Xiao, Z Jia, L Guo… - Cell host & …, 2020 - cell.com
The outbreaks of 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
infection have posed a severe threat to global public health. It is unclear how the human …

Unraveling the mystery of Covid‐19 cytokine storm: from skin to organ systems

S Garg, M Garg, N Prabhakar, P Malhotra… - Dermatologic …, 2020 - Wiley Online Library
COVID‐19 is a global pandemic that emerged from Wuhan, China. Besides pneumonia and
acute respiratory distress syndrome, the disease leads to multisystem involvement in the …