The longitudinal immune response to coronavirus disease 2019: chasing the cytokine storm

AS Chau, AG Weber, NI Maria, S Narain… - Arthritis & …, 2021 - Wiley Online Library
The clinical progression of the severe acute respiratory syndrome coronavirus 2 infection,
coronavirus 2019 (COVID‐19), to critical illness is associated with an exaggerated immune …

[HTML][HTML] SARS–CoV-2 immuno-pathogenesis and potential for diverse vaccines and therapies: opportunities and challenges

AR McGill, R Khalil, R Dutta, R Green, M Howell… - Infectious Disease …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel coronavirus
that emerged from Wuhan, China in late 2019 causing coronavirus disease-19 (COVID-19) …

[HTML][HTML] Lung histopathological findings in COVID-19 disease–a systematic review

G Pannone, VCA Caponio, IS De Stefano… - Infectious Agents and …, 2021 - Springer
Since December 2019, the global burden of the COVID-19 pandemic has increased rapidly
and has impacted nearly every country in the world, affecting those who are elderly or with …

Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
As a zoonotic disease that has already spread globally to several million human beings and
possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) …

[HTML][HTML] Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

A Aslan, C Aslan, NM Zolbanin, R Jafari - Pneumonia, 2021 - Springer
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

[HTML][HTML] Immune Response and COVID-19: A mirror image of Sepsis

E López-Collazo, J Avendano-Ortiz… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 virus and its associated disease COVID-19 have triggered
significant threats to public health, in addition to political and social changes. An important …

[HTML][HTML] Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

[HTML][HTML] SARS-CoV-2: pathogenesis, and advancements in diagnostics and treatment

K Khalaf, N Papp, JTT Chou, D Hana… - Frontiers in …, 2020 - frontiersin.org
The emergence and rapid spread of SARS-CoV-2 in December 2019 has brought the world
to a standstill. While less pathogenic than the 2002–2003 SARS-CoV, this novel …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
With the objective of linking early findings relating to the novel SARS-CoV-2 coronavirus
with potentially informative findings from prior research literature and to promote …