In humans, the plasma level of sex hormone binding globulin (SHBG) is regulated by
several hormones. We have now accumulated evidence that SHBG is also intimately related …

It is known that there is an inverse relationship between the serum levels of insulin and sex
hormone-binding globulin (SHBG) in women, but the relationship in men has not been …

This study was undertaken to investigate the relationship of the serum sex hormone-binding
globulin (SHBG) levels with the plasma insulin concentration and with the insulin resistance …

Although sex steroids have long been known to influence serum concentrations of SHBG, it
is now recognized that nutritional factors may be more important in the regulation of SHBG in …

Insulin has emerged as a regulator of sex hormone-binding globulin (SHBG) production in
vitro and in vivo. A role for insulin in regulating SHBG exists in insulin resistant states such …

The level of sex hormone-binding globulin (SHBG) is associated with glucose metabolism in
nondiabetic women and men, and the finding of low SHBG levels is suggested to be a …

Sex hormone-binding globulin (SHBG) is a plasma glycoprotein with high binding affinity for
testosterone and dihydrotestosterone and lower affinity for estradiol. SHBG is synthesized in …

Sex hormone binding globulin (SHBG) is a specific steroid-binding plasma glycoprotein
regulated by several factors. Sex steroids are currently considered to be the main …

In this review, the different factors known to affect SHBG levels are discussed with respect to
their possible significance in the physiological regulation of this protein: Sex steroids …

The high-affinity binding of the sex hormone-binding globulin (SHBG) for testosterone and to
a lesser extent for estradiol influences the circulating levels of these sex steroid hormones …