A Lassa fever live-attenuated vaccine based on codon deoptimization of the viral glycoprotein gene
Lassa virus (LASV) is endemic in Western Africa and is estimated to infect hundreds of
thousands of individuals annually. A considerable number of these infections result in Lassa …
thousands of individuals annually. A considerable number of these infections result in Lassa …
A Lassa virus live-attenuated vaccine candidate based on rearrangement of the intergenic region
Lassa virus (LASV) poses a significant public health problem within the regions of Lassa
fever endemicity in Western Africa. LASV infects several hundred thousand individuals …
fever endemicity in Western Africa. LASV infects several hundred thousand individuals …
A Lassa virus live attenuated vaccine candidate that is safe and efficacious in guinea pigs
Lassa virus (LASV) is a rodent-borne mammarenavirus that causes tens to hundreds of
thousands of human infections annually in Western Africa. Approximately 20% of these …
thousands of human infections annually in Western Africa. Approximately 20% of these …
Lassa virus-like particles displaying all major immunological determinants as a vaccine candidate for Lassa hemorrhagic fever
LM Branco, JN Grove, FJ Geske, ML Boisen, IJ Muncy… - Virology journal, 2010 - Springer
Background Lassa fever is a neglected tropical disease with significant impact on the health
care system, society, and economy of Western and Central African nations where it is …
care system, society, and economy of Western and Central African nations where it is …
Protection from lethal Lassa disease can be achieved both before and after virus exposure by administration of single-cycle replicating Lassa virus replicon particles
Lassa fever is a frequently severe human disease that is endemic to several countries in
West Africa. To date, no licensed vaccines are available to prevent Lassa virus (LASV) …
West Africa. To date, no licensed vaccines are available to prevent Lassa virus (LASV) …
Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments
HL Murphy, H Ly - Virulence, 2021 - Taylor & Francis
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
[HTML][HTML] Vaccine platforms for the prevention of Lassa fever
J Purushotham, T Lambe, SC Gilbert - Immunology Letters, 2019 - Elsevier
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV), which is
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …
Prospects of Lassa fever candidate vaccines
BI Ademusire, K Wieczorek, AT Alonge, A Rajen… - African Journal of …, 2022 - ajol.info
Ademusire et al., Afr., J. Infect. Dis. (2022) 16 (2S) 46 -58 https://doi.org/10.21010/Ajid v16i2S.6
PROSPECTS OF LASSA FEVER Page 1 Ademusire et al., Afr., J. Infect. Dis. (2022) 16 (2S) 46 …
PROSPECTS OF LASSA FEVER Page 1 Ademusire et al., Afr., J. Infect. Dis. (2022) 16 (2S) 46 …
[HTML][HTML] Lassa virus diversity and feasibility for universal prophylactic vaccine
IS Lukashevich, S Paessler, JC de la Torre - F1000Research, 2019 - ncbi.nlm.nih.gov
Lassa virus (LASV) is a highly prevalent mammarenavirus in West Africa and is maintained
in nature in a persistently infected rodent host, Mastomys natalensis, which is widely spread …
in nature in a persistently infected rodent host, Mastomys natalensis, which is widely spread …
Combating Lassa fever in West African sub-region: Progress, challenges, and future perspectives
Lassa fever (LF) is a rodent-borne disease that threatens human health in the sub-region of
West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently …
West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently …