A prognostic model for glioblastoma patients treated with standard therapy based on a prospective cohort of consecutive non-selected patients from a single institution

AA Abedi, K Grunnet, IJ Christensen… - Frontiers in …, 2021 - frontiersin.org
Background Glioblastoma patients administered standard therapies, comprising maximal
surgical resection, radiation therapy with concomitant and adjuvant temozolomide, have a …

Progression-free survival as a surrogate endpoint for overall survival in glioblastoma: a literature-based meta-analysis from 91 trials

K Han, M Ren, W Wick, L Abrey, A Das, J Jin… - Neuro …, 2014 - academic.oup.com
Background The aim of this study was to determine correlations between progression-free
survival (PFS) and the objective response rate (ORR) with overall survival (OS) in …

Association of patterns of care, prognostic factors, and use of radiotherapy–temozolomide therapy with survival in patients with newly diagnosed glioblastoma: a …

P Fabbro-Peray, S Zouaoui, A Darlix, M Fabbro… - Journal of Neuro …, 2019 - Springer
Background Glioblastoma is the most frequent primary malignant brain tumor. In daily
practice and at whole country level, oncological care management for glioblastoma patients …

Survival effect of first-and second-line treatments for patients with primary glioblastoma: a cohort study from a prospective registry, 1997–2010

F Nava, I Tramacere, A Fittipaldo, MG Bruzzone… - Neuro …, 2014 - academic.oup.com
Background Prospective follow-up studies of large cohorts of patients with glioblastoma
(GBM) are needed to assess the effectiveness of conventional treatments in clinical practice …

Clinical variables serve as prognostic factors in a model for survival from glioblastoma multiforme: an observational study of a cohort of consecutive non-selected …

SR Michaelsen, IJ Christensen, K Grunnet… - BMC cancer, 2013 - Springer
Background Although implementation of temozolomide (TMZ) as a part of primary therapy
for glioblastoma multiforme (GBM) has resulted in improved patient survival, the disease is …

What predicts survival in glioblastoma? A population-based study of changes in clinical management and outcome

B Fekete, K Werlenius, M Tisell, A Pivodic… - Frontiers in …, 2023 - frontiersin.org
Background Glioblastoma is the most common and most aggressive primary brain tumor in
adults. Despite multimodal treatment, the median survival time is 15–16 months and 5-year …

Long-term trends in glioblastoma survival: implications for historical control groups in clinical trials

S Sheikh, T Radivoyevitch… - Neuro-Oncology …, 2020 - academic.oup.com
Background Historical controls continue to be used in early-phase brain tumor trials. We aim
to show that historical changes in survival trends for glioblastoma (GBM) call into question …

Nomograms for predicting survival of patients with newly diagnosed glioblastoma: prognostic factor analysis of EORTC and NCIC trial 26981-22981/CE. 3

T Gorlia, MJ van den Bent, ME Hegi… - The lancet …, 2008 - thelancet.com
Background A randomised trial published by the European Organisation for Research and
Treatment of Cancer (EORTC) and the National Cancer Institute of Canada (NCIC) Clinical …

Prognostic factors for glioblastoma patients–a clinical population‐based study

B Fekete, K Werlenius, C Örndal… - Acta Neurologica …, 2016 - Wiley Online Library
Objectives To address in a retrospective and population‐based study prognostic factors for
survival time after diagnosis and surgery for glioblastoma multiforme (GBM). Material and …

Survival outcomes and prognostic factors in glioblastoma

NF Brown, D Ottaviani, J Tazare, J Gregson, N Kitchen… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common tumour that originates in the brain in
adults. Most of the published data on glioblastoma are from patients in clinical trials who …