Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease

M Khrom, M Long, S Dube, L Robbins, GJ Botwin… - Gastroenterology, 2024 - Elsevier
Background & Aims Patients with inflammatory bowel disease (IBD) frequently develop
extraintestinal manifestations (EIMs) that contribute substantially to morbidity. We assembled …

Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathways

S van Sommeren, M Janse, J Karjalainen… - Inflammatory bowel …, 2014 - academic.oup.com
Background The clinical presentation of the inflammatory bowel diseases (IBD) is extremely
heterogenous and is characterized by various extraintestinal manifestations and …

Extraintestinal manifestations in inflammatory bowel disease–epidemiology, genetics, and pathogenesis

T Greuter, SR Vavricka - Expert review of gastroenterology & …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, primarily
of, but not restricted to the gut. Extraintestinal manifestations (EIMs) are frequently observed …

Transcriptome-wide association study for inflammatory bowel disease reveals novel candidate susceptibility genes in specific colon subsites and tissue categories

V Díez-Obrero, F Moratalla-Navarro… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Genome-wide association studies [GWAS] for inflammatory
bowel disease [IBD] have identified 240 risk variants. However, the benefit of understanding …

Familial risk of inflammatory bowel disease: a population-based cohort study 1977–2011

FT Moller, V Andersen, J Wohlfahrt… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Estimates of familial risk of inflammatory bowel diseases (IBDs), Crohn's
disease (CD), and ulcerative colitis (UC) are needed for counseling of patients and could be …

[HTML][HTML] Susceptibility gene profiling elucidates the pathogenesis of inflammatory bowel disease and provides precision medicine

H Gao, R Liu, H Huang, Z Liu - Clinical and Translational Medicine, 2023 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) are characterized by idiopathic chronic inflammation of
the gastrointestinal tract, comprising the two major entities ulcerative colitis (UC) and …

Genetic susceptibility to inflammatory bowel disease: should we be looking to the hypothalamus?

A Dal Buono, D Caldirola, M Allocca - Expert Review of Clinical …, 2021 - Taylor & Francis
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), are progressive and disabling inflammatory disorders of the intestine. The precise …

Inflammatory bowel diseases

VK Denmark, L Mayer - The Autoimmune Diseases, 2014 - Elsevier
Inflammatory bowel disease (IBD) is comprised of Crohn's disease (CD), characterized by
transmural inflammation involving the entire GI tract and ulcerative colitis (UC), which …

Immuno-genomic profiling of patients with inflammatory bowel disease: a systematic review of genetic and functional in vivo studies of implicated genes

T Coelho, G Andreoletti, JJ Ashton… - Inflammatory bowel …, 2014 - academic.oup.com
Background Over the last 2 decades, there has been an ever-expanding catalog of genetic
variants implicated in inflammatory bowel disease (IBD) through genome-wide association …

Development of extraintestinal manifestations in pediatric patients with inflammatory bowel disease

FA Jose, EA Garnett, E Vittinghoff… - Inflammatory bowel …, 2009 - academic.oup.com
Background Extraintestinal manifestations (EIMs) in pediatric patients with inflammatory
bowel disease (IBD) are poorly characterized. We examined the prevalence of EIMs at …