Standardization of blood collection and processing for the diagnostic use of extracellular vesicles

M Venturella, FM Carpi, D Zocco - Current Pathobiology Reports, 2019 - Springer
Abstract Purpose of Review Extracellular vesicles (EVs) are lipid membrane vesicles
released by many types of cells in both health and disease. EVs can be found in most body …

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

A Clayton, E Boilard, EI Buzas, L Cheng… - Journal of …, 2019 - Taylor & Francis
There is an increasing interest in exploring clinically relevant information that is present in
body fluids, and extracellular vesicles (EVs) are intrinsic components of body fluids (“liquid …

In vitro diagnostic technologies for the detection of extracellular vesicles: current status and future directions

S Song, L Zhu, C Wang, Y Yang - View, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are natural vehicles carrying and transferring bioactive
molecules for intercellular communication and play key roles in physiological and …

Applicability of extracellular vesicles in clinical studies

D Vozel, B Uršič, JL Krek, R Štukelj… - European Journal of …, 2017 - Wiley Online Library
Background Extracellular vesicles (EV s) are submicron cellular fragments that mediate
intercellular communication. EV s have in the last decade attracted major interest as …

Isolation of circulating extracellular vesicles by high-performance size-exclusion chromatography

K Takov, IJ Teng, M Mayr - Extracellular Vesicles in Diagnosis and Therapy, 2022 - Springer
Circulating extracellular vesicles (EVs) are gaining increased attention as carriers of
proteins, nucleic acids, and lipids. Blood contains EVs from different cell sources that …

Clinical applications and challenges in the field of extracellular vesicles

R Nieuwland, A Enciso-Martinez, JWP Bracht - Medizinische Genetik, 2023 - degruyter.com
Body fluids contain cell-derived particles called extracellular vesicles (EVs). EVs are
released by cells and are present in all body fluids (ie liquid biopsies). EVs contribute to …

A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity

X Zhang, EGF Borg, AM Liaci, HR Vos… - Journal of extracellular …, 2020 - Taylor & Francis
Extracellular vesicles (EV) are membrane encapsulated nanoparticles that can function in
intercellular communication, and their presence in biofluids can be indicative for (patho) …

Extracellular vesicle separation techniques impact results from human blood samples: considerations for diagnostic applications

T Tzaridis, D Bachurski, S Liu, K Surmann… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are reminiscent of their cell of origin and thus represent a
valuable source of biomarkers. However, for EVs to be used as biomarkers in clinical …

[HTML][HTML] Diagnostic and prognostic potential of extracellular vesicles in peripheral blood

ALS Revenfeld, R Bæk, MH Nielsen, A Stensballe… - Clinical …, 2014 - Elsevier
Abstract Purpose Extracellular vesicles (EVs) are small, membrane-enclosed entities
released from cells in many different biological systems. These vesicles play an important …

Toward routine detection of extracellular vesicles in clinical samples

R Van der Meel, M Krawczyk‐Durka… - … journal of laboratory …, 2014 - Wiley Online Library
The majority, if not all, of human cell types secrete extracellular vesicles (EVs) into their
environment, at least partly as a means of intercellular communication. These secreted …