Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications

N Ferrara - Seminars in oncology, 2002 - Elsevier
Angiogenesis, or formation of new blood vessels from pre-existing ones, is essential for
normal development and wound healing/reproductive functions in adults. Abnormal …

[HTML][HTML] Vascular endothelial growth factor (VEGF) and its role in non-endothelial cells: autocrine signalling by VEGF

AM Duffy, DJ Bouchier-Hayes… - Madame Curie …, 2013 - ncbi.nlm.nih.gov
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor and was first
described as an essential growth factor for vascular endothelial cells. VEGF is up-regulated …

Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy

S Takahashi - Biological and Pharmaceutical Bulletin, 2011 - jstage.jst.go.jp
Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) have crucial roles in
both physiological and pathological angiogenesis. The VEGF family consists of VEGF-A …

VEGFs, receptors and angiogenesis

T Veikkola, K Alitalo - Seminars in cancer biology, 1999 - Elsevier
Angiogenesis, the formation of new blood vessels from pre–-existing ones, is central for both
normal development and homeostasis as well as in certain pathological conditions. The …

Vascular endothelial growth factor (VEGF) and its receptors

G Neufeld, T Cohen, S Gengrinovitch… - The FASEB …, 1999 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …

[HTML][HTML] Biology of vascular endothelial growth factors

H Roy, S Bhardwaj, S Ylä-Herttuala - FEBS letters, 2006 - Elsevier
Angiogenesis is the process by which new blood vessels are formed from existing vessels.
The vascular endothelial growth factors (VEGFs) are considered as key molecules in the …

Novel vegf family members: Vegf-b, vegf-c and vegf-d

X Li, U Eriksson - The international journal of biochemistry & cell biology, 2001 - Elsevier
Vascular endothelial growth factors (VEGFs) constitute a group of structurally and
functionally related growth factors that modulate many important physiological functions of …

Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis

P Gerwins, E Sköldenberg… - Critical reviews in oncology …, 2000 - Elsevier
Angiogenesis, formation of new vessels from pre-existing ones, results from stimulation of
endothelial cells, which line the vessel wall. These cells will leave their resting state and …

VEGF receptor signal transduction

T Matsumoto, L Claesson-Welsh - Science's STKE, 2001 - science.org
The family of vascular endothelial growth factors (VEGFs) currently includes VEGF-A,-B,-C,-
D,-E, and placenta growth factor (PlGF). Several of these factors, notably VEGF-A, exist as …

VEGF receptor signaling and endothelial function

S Kliche, J Waltenberger - IUBMB life, 2001 - Wiley Online Library
Angiogenesis, the formation of new blood vessels from preexisting ones, is a central process
during normal development and during pathological repair. Vascular endothelial growth …