Looking into the IL-1 of the storm: are inflammasomes the link between immunothrombosis and hyperinflammation in cytokine storm syndromes?
TA Gleeson, E Nordling, C Kaiser… - Discovery …, 2022 - academic.oup.com
Inflammasomes and the interleukin (IL)-1 family of cytokines are key mediators of both
inflammation and immunothrombosis. Inflammasomes are responsible for the release of the …
inflammation and immunothrombosis. Inflammasomes are responsible for the release of the …
Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis
LK Weaver, EM Behrens - Current treatment options in rheumatology, 2017 - Springer
Opinion statement Cytokine storm syndromes require rapid diagnosis and treatment to limit
the morbidity and mortality caused by the hyperinflammatory state that characterizes these …
the morbidity and mortality caused by the hyperinflammatory state that characterizes these …
The 'cytokine storm': molecular mechanisms and therapeutic prospects
R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …
Inflammasome-dependent coagulation activation in sepsis
Sepsis is a potentially life-threatening, pathological condition caused by a dysregulated host
response to infection. Pathologically, systemic inflammation can initiate coagulation …
response to infection. Pathologically, systemic inflammation can initiate coagulation …
Highways to hell: Mechanism-based management of cytokine storm syndromes
Since the first textbook devoted to cytokine storm syndromes (CSSs) was published in 2019,
the world has changed dramatically and the term's visibility has broadened. Herein, we …
the world has changed dramatically and the term's visibility has broadened. Herein, we …
Inflammasome-dependent cytokines at the crossroads of health and autoinflammatory disease
H Van Gorp, N Van Opdenbosch… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
As key regulators of both innate and adaptive immunity, it is unsurprising that the activity of
interleukin (IL)-1 cytokine family members is tightly controlled by decoy receptors …
interleukin (IL)-1 cytokine family members is tightly controlled by decoy receptors …
Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation
AK Mankan, A Kubarenko… - Clinical & Experimental …, 2012 - academic.oup.com
Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW
SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases …
SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases …
The multifaceted immunology of cytokine storm syndrome
Cytokine storm syndromes (CSSs) are potentially fatal hyperinflammatory states that share
the underpinnings of persistent immune cell activation and uninhibited cytokine production …
the underpinnings of persistent immune cell activation and uninhibited cytokine production …
Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes
VU Ozkurede, L Franchi - Clinical & Experimental Immunology, 2012 - academic.oup.com
Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW
SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases …
SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases …
[HTML][HTML] Inflammasome activation triggers blood clotting and host death through pyroptosis
Inflammasome activation and subsequent pyroptosis are critical defense mechanisms
against microbes. However, overactivation of inflammasome leads to death of the host …
against microbes. However, overactivation of inflammasome leads to death of the host …