Purpose A prospective randomized trial in small-cell lung cancer (SCLC) was performed to
determine if intensification of the platinum dose by giving cisplatin and carboplatin in …

Abstract From April, 1979 to November, 1981, 293 patients with small cell lung carcinoma
(SCLC) were entered on a randomized, controlled study comparing the two induction …

One hundred and twelve patients with small cell lung cancer (SCLC) were treated with a
combination (CAVE) of cisplatin (60 mg/m 2 day 1), adriamycin (45 mg/m 2 day 1), etoposide …

One hundred forty-seven eligible patients with small-cell carcinoma of the lung (SCCL) have
been randomized to receive alternating (A) or sequential (S) combination chemotherapy …

Four patients with limited disease small cell carcinoma of the lung were treated with high-
dose cyclophosphamide (120 mg/kg over days 1 and 2), BCNU (400 mg/m 2 over days 1 …

This randomised trial compared platinum-based to anthracycline-based chemotherapy in
patients with small-cell lung cancer (limited or extensive stage) and⩽ 2 adverse prognostic …

Thirty-four previously untreated patients with extensive small cell lung cancer were treated
with a combination of carboplatin 300 mg m-2 iv on day 1 and etoposide 100 mg m-2 iv on …

Cisplatin plus VP-16 has become a widely used salvage regimen for CAV
(cyclophosphamide, doxorubicin [Adriamycin], and vincristine) failures. However, the major …

A multicentric randomized prospective trial was conducted to test whether late intensification
chemotherapy would increase the remission rate, the relapse-free survival, and the survival …

Purpose: To assess the efficacy and toxicity of carboplatin, etoposide, and exisulind as initial
therapy for extensive stage small cell lung cancer. Patients and Methods: The Cancer and …