Intriguing findings on genetic and environmental causation suggest a need to reframe the
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …

Background: Much of what we thought we knew about genetics needs to be modified in light
of recent discoveries. What are the implications of these advances for identifying genes …

Child maltreatment in the family context is a prevalent and pervasive phenomenon in many
modern societies. The global perpetration of child abuse and neglect stands in stark contrast …

Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …

Abstract Objective. In 1998, Felitti and colleagues published the first study of the Adverse
Childhood Experiences-Questionnaire (ACE-Q), a 10-item scale used to correlate childhood …

The association between childhood adversity (CA) and psychosis has been extensively
investigated in recent years. An increasing body of research has also focused on the …

Objective The immediate impact of child maltreatment on health and developmental
trajectories over time is unknown. Longitudinal studies starting in the direct aftermath of …

Objective To understand whether genetic risk for attention-deficit/hyperactivity disorder
(ADHD) is associated with the course of the disorder across childhood and into young …

Background Child maltreatment is associated with cardiovascular disease (CVD), but
mediation pathways have not been fully elucidated. The aim of the current study was to …

Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …