An integrated biopsychosocial model of childhood maltreatment and psychosis

V Barker, A Gumley, M Schwannauer… - The British Journal of …, 2015 - cambridge.org
There is now a well-established link between childhood maltreatment and psychosis. It is,
however, unclear what the mechanisms are by which this occurs. Here, we propose a …

[HTML][HTML] Associations between abuse/neglect and ADHD from childhood to young adulthood: A prospective nationally-representative twin study

A Stern, J Agnew-Blais, A Danese, HL Fisher… - Child abuse & …, 2018 - Elsevier
Child maltreatment has consistently been found to be associated with attention
deficit/hyperactivity disorder (ADHD). However, the robustness of this association and the …

Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population

PR Jansen, TJC Polderman, K Bolhuis… - Journal of Child …, 2018 - Wiley Online Library
Background Genome‐wide association studies in adults have identified numerous genetic
variants related to psychiatric disorders and related traits, such as schizophrenia and …

Objective and subjective experiences of child maltreatment and their relationships with psychopathology

A Danese, CS Widom - Nature human behaviour, 2020 - nature.com
Does psychopathology develop as a function of the objective or subjective experience of
childhood maltreatment? To address this question, we studied a unique cohort of 1,196 …

[HTML][HTML] Gene-environment interaction in evolutionary perspective: differential susceptibility to environmental influences

J Belsky, S Hartman - World Psychiatry, 2014 - ncbi.nlm.nih.gov
By tradition, psychiatrists have been concerned with the nature, origins, sequelae and
treatment of mental disorders. When it comes to etiology and the role of genetics, psychiatric …

Childhood maltreatment and attention deficit hyperactivity disorder symptoms in adults: a large twin study

AJ Capusan, R Kuja-Halkola, P Bendtsen… - Psychological …, 2016 - cambridge.org
BackgroundChildhood maltreatment (CM) has been associated with increased risk of
attention deficit hyperactivity disorder (ADHD) in children and adults. It is, however, unclear …

Understanding the relative contributions of direct environmental effects and passive genotype–environment correlations in the association between familial risk factors …

MA Bornovalova, JR Cummings, E Hunt… - Psychological …, 2014 - cambridge.org
BackgroundPrevious work reports an association between familial risk factors stemming
from parental characteristics and offspring disruptive behavior disorders (DBDs). This …

Pathways linking childhood maltreatment and adult physical health

MO Min, S Minnes, H Kim, LT Singer - Child abuse & neglect, 2013 - Elsevier
OBJECTIVES: This study examined whether a self-reported history of childhood
maltreatment (physical, emotional, and sexual abuse and physical and emotional neglect) is …

Associations between objective and subjective experiences of childhood maltreatment and the course of emotional disorders in adulthood

A Danese, CS Widom - JAMA psychiatry, 2023 - jamanetwork.com
Importance A history of childhood maltreatment is associated with an unfavorable course of
illness for emotional disorders. However, the origins and mechanisms underlying these …

The subjective experience of childhood maltreatment in psychopathology

A Danese, CS Widom - JAMA psychiatry, 2021 - jamanetwork.com
Childhood maltreatment is a key risk factor for lifecourse psychopathology. However, the
nature of this association remains unclear. Professionals working with young people who …