Natural killer cells: potential biomarkers and therapeutic target in autoimmune diseases?

E Gianchecchi, DV Delfino, A Fierabracci - Frontiers in immunology, 2021 - frontiersin.org
Autoimmune diseases recognize a multifactorial pathogenesis, although the exact
mechanism responsible for their onset remains to be fully elucidated. Over the past few …

Natural killer cells in human autoimmune diseases

N Schleinitz, F Vély, JR Harlé, E Vivier - Immunology, 2010 - Wiley Online Library
Natural killer (NK) cells have been implicated in tumour surveillance and in the early control
of several microbial infections. In autoimmune disease their involvement in these processes …

The role of natural killer cells in autoimmune diseases

UC Kucuksezer, E Aktas Cetin, F Esen… - Frontiers in …, 2021 - frontiersin.org
Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

Natural killer cells in human autoimmunity

M Flodström-Tullberg, YT Bryceson, FD Shi… - Current opinion in …, 2009 - Elsevier
Natural killer (NK) cells are innate immune cells. Although NK cells are best characterized
for their ability to control tumors and infections, recent data have indicated that they also are …

NK cells: elusive players in autoimmunity

S Johansson, L Berg, H Hall, P Höglund - Trends in immunology, 2005 - cell.com
Natural killer (NK) cells were once regarded as relatively simple cells of the innate immune
system. However, they are now revealing themselves as multifunctional regulatory cells that …

NK cells in autoimmune diseases: protective or pathogenic?

M Liu, S Liang, C Zhang - Frontiers in Immunology, 2021 - frontiersin.org
Autoimmune diseases generally result from the loss of self-tolerance (ie, failure of the
immune system to distinguish self from non-self), and are characterized by autoantibody …

NK cell subsets in autoimmune diseases

C Zhang, Z Tian - Journal of Autoimmunity, 2017 - Elsevier
Natural killer (NK) cells are lymphocytes of the innate immune system. They not only exert
cell-mediated cytotoxicity against tumor cells or infected cells, but also play regulatory role …

Natural killer cells as indispensable players and therapeutic targets in autoimmunity

FD Shi, Q Zhou - Autoimmunity, 2011 - Taylor & Francis
Natural killer (NK) cells of the innate immune system are equipped with a cytolytic machinery
and produce cytokines, which enable these cells to profoundly modify adaptive immune …

NK cells in autoimmunity: a two-edg'd weapon of the immune system

R Perricone, C Perricone, C De Carolis… - Autoimmunity reviews, 2008 - Elsevier
Natural killer (NK) cells are part of the innate-immune system and respond rapidly to a
variety of insults via cytokine secretion and cytolytic activity. Their main function is first line of …

Natural killer cells in inflammatory autoimmune diseases

Y Yang, J Day… - Clinical & …, 2021 - Wiley Online Library
Natural killer (NK) cells are a specialised population of innate lymphoid cells (ILCs) that help
control local immune responses. Through natural cytotoxicity, production of cytokines and …