Emerging roles for extracellular vesicles in tissue engineering and regenerative medicine

TN Lamichhane, S Sokic, JS Schardt… - … Engineering Part B …, 2015 - liebertpub.com
Extracellular vesicles (EVs)—comprising a heterogeneous population of cell-derived lipid
vesicles including exosomes, microvesicles, and others—have recently emerged as both …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Extracellular vesicles in tissue engineering: biology and engineered strategy

Z Pan, W Sun, Y Chen, H Tang, W Lin… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EVs), acting as an important ingredient of intercellular communication
through paracrine actions, have gained tremendous attention in the field of tissue …

Stem cell extracellular vesicles: extended messages of regeneration

M Riazifar, EJ Pone, J Lötvall… - Annual review of …, 2017 - annualreviews.org
Stem cells are critical to maintaining steady-state organ homeostasis and regenerating
injured tissues. Recent intriguing reports implicate extracellular vesicles (EVs) as carriers for …

Engineering extracellular vesicles as nanotherapeutics for regenerative medicine

L Ramasubramanian, P Kumar, A Wang - Biomolecules, 2019 - mdpi.com
Long thought of to be vesicles that primarily recycled waste biomolecules from cells,
extracellular vesicles (EVs) have now emerged as a new class of nanotherapeutics for …

Extracellular vesicles in regenerative medicine: potentials and challenges

JY Lee, HS Kim - Tissue engineering and regenerative medicine, 2021 - Springer
The ultimate goal of regenerative medicine is to regain or restore the damaged or lost
function of tissues and organs. Several therapeutic strategies are currently being explored to …

Recent advances in extracellular vesicle engineering and its applications to regenerative medicine

WK Rhim, JY Kim, SY Lee, SG Cha, JM Park… - Biomaterials …, 2023 - spj.science.org
Extracellular vesicles (EVs) are nanosized particles that are released from cells and reflect
the characteristics of the mother cell. Recently, the EVs have been used in several types of …

Functional extracellular vesicles for regenerative medicine

HY Kim, S Kwon, W Um, S Shin, CH Kim, JH Park… - Small, 2022 - Wiley Online Library
The unique biological characteristics and promising clinical potential of extracellular
vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as …

Extracellular vesicles: potential roles in regenerative medicine

OG De Jong, BWM Van Balkom… - Frontiers in …, 2014 - frontiersin.org
Extracellular vesicles (EV) consist of exosomes, which are released upon fusion of the
multivesicular body with the cell membrane, and microvesicles, which are released directly …

Therapeutic advances of stem cell-derived extracellular vesicles in regenerative medicine

L Yin, X Liu, Y Shi, DKW Ocansey, Y Hu, X Li, C Zhang… - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs), which are the main paracrine components of stem cells, mimic
the regenerative capacity of these cells. Stem cell-derived EVs (SC-EVs) have been used for …