The proteomic characteristics of airway mucus from critical ill COVID-19 patients

Z Zhang, T Wang, F Liu, A Zhu, G Gu, J Luo, J Xu… - Life Sciences, 2021 - Elsevier
Background The pandemic of the coronavirus disease 2019 (COVID-19) has brought a
global public health crisis. However, the pathogenesis underlying COVID-19 are barely …

[HTML][HTML] Proteomic profiling reveals a distinctive molecular signature for critically ill COVID-19 patients compared with asthma and chronic obstructive pulmonary …

Z Zhang, F Lin, F Liu, Q Li, Y Li, Z Zhu, H Guo… - International Journal of …, 2022 - Elsevier
Objective The mortality rate for critically ill COVID-19 cases was more than 80%.
Nonetheless, research about the effect of common respiratory diseases on critically ill …

Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples

L Leng, R Cao, J Ma, D Mou, Y Zhu, W Li, L Lv… - … and Targeted Therapy, 2020 - nature.com
The COVID-19 pandemic has emerged as a global health emergency due to its association
with severe pneumonia and relative high mortality. However, the molecular characteristics …

Proteomic lung analysis revealed hyper-activation of neutrophil extracellular trap formation in cases of fatal COVID-19

S Song, L Zeng, J Xu, L Shi, L Lu, Y Ling, L Zhang - Heliyon, 2024 - cell.com
The molecular pathology of lung injury in patients with Corona Virus Disease 2019 (COVID-
19) remain unclear. In this study, we performed a proteomic study of lung tissues from seven …

Proteomic characteristics of bronchoalveolar lavage fluid in critical COVID‐19 patients

HL Zeng, D Chen, J Yan, Q Yang, QQ Han… - The FEBS …, 2021 - Wiley Online Library
Up to 10–20% of patients with coronavirus disease 2019 (COVID‐19) develop a severe
pulmonary disease due to immune dysfunction and cytokine dysregulation. However, the …

COVID-19 Salivary Protein Profile: Unravelling Molecular Aspects of SARS-CoV-2 Infection

E Esteves, VM Mendes, B Manadas, R Lopes… - Journal of Clinical …, 2022 - mdpi.com
COVID-19 is the most impacting global pandemic of all time, with over 600 million infected
and 6.5 million deaths worldwide, in addition to an unprecedented economic impact …

Proteomic Analysis of Salivary Extracellular Vesicles from COVID-19 Patients Reveals a Specific Anti-COVID-19 Response Protein Signature

L Weber, A Torres, O Realini, MJ Bendek… - International Journal of …, 2024 - mdpi.com
Despite the understanding of the coronavirus disease-19 (COVID-19), the role of salivary
extracellular vesicles (sEVs) in COVID-19 remains unclear. Exploring the proteomic cargo of …

Human bronchial-pulmonary proteomics in coronavirus disease 2019 (COVID-19) pandemic: applications and implications

HW Tan, YM Xu, ATY Lau - Expert Review of Proteomics, 2021 - Taylor & Francis
Introduction The outbreak of the newly discovered human coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has disrupted the normal life of almost …

Noninvasive nasopharyngeal proteomics of COVID-19 patient identify abnormalities related to complement and coagulation cascade and mucosal immune system

MA Ayass, W Cao, J Zhang, J Dai, K Zhu, T Tripathi… - Plos one, 2022 - journals.plos.org
Serum or plasma have been the primary focus of proteomics studies for COVID-19 to identity
biomarkers and potential drug targets. The nasal mucosal environment which consists of …

Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis

E Moreno, S Ciordia, SM Fátima, D Jiménez… - Clinical Proteomics, 2024 - Springer
Background Information on the microbiome's human pathways and active members that can
affect SARS-CoV-2 susceptibility and pathogenesis in the salivary proteome is very scarce …