Proteomic blood profiling in mild, severe and critical COVID-19 patients
The recent SARS-CoV-2 pandemic manifests itself as a mild respiratory tract infection in
most individuals, leading to COVID-19 disease. However, in some infected individuals, this …
most individuals, leading to COVID-19 disease. However, in some infected individuals, this …
In-depth blood proteome profiling analysis revealed distinct functional characteristics of plasma proteins between severe and non-severe COVID-19 patients
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over forty
million patients worldwide. Although most coronavirus disease 2019 (COVID-19) patients …
million patients worldwide. Although most coronavirus disease 2019 (COVID-19) patients …
Longitudinal plasma proteomics analysis reveals novel candidate biomarkers in acute COVID-19
Y Mohammed, DR Goodlett, MP Cheng… - Journal of proteome …, 2022 - ACS Publications
The host response to COVID-19 pathophysiology over the first few days of infection remains
largely unclear, especially the mechanisms in the blood compartment. We report on a …
largely unclear, especially the mechanisms in the blood compartment. We report on a …
Plasma proteomics identify biomarkers and pathogenesis of COVID-19
T Shu, W Ning, D Wu, J Xu, Q Han, M Huang, X Zou… - Immunity, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic is a global public health
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …
Characterization by quantitative serum proteomics of immune-related prognostic biomarkers for COVID-19 symptomatology
The COVID-19 pandemic caused by SARS-CoV-2 challenges the understanding of factors
affecting disease progression and severity. The identification of prognostic biomarkers and …
affecting disease progression and severity. The identification of prognostic biomarkers and …
Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach
Y Kimura, Y Nakai, J Shin, M Hara, Y Takeda, S Kubo… - Scientific reports, 2021 - nature.com
The COVID-19 pandemic is an unprecedented threat to humanity that has provoked global
health concerns. Since the etiopathogenesis of this illness is not fully characterized, the …
health concerns. Since the etiopathogenesis of this illness is not fully characterized, the …
Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia
Background COVID-19 remains a major public health challenge, requiring the development
of tools to improve diagnosis and inform therapeutic decisions. As dysregulated …
of tools to improve diagnosis and inform therapeutic decisions. As dysregulated …
Serum protein profiling reveals a landscape of inflammation and immune signaling in early-stage COVID-19 infection
X Hou, X Zhang, X Wu, M Lu, D Wang, M Xu… - Molecular & Cellular …, 2020 - ASBMB
Coronavirus disease 2019 (COVID-19) is a highly contagious infection and threating the
human lives in the world. The elevation of cytokines in blood is crucial to induce cytokine …
human lives in the world. The elevation of cytokines in blood is crucial to induce cytokine …
A multi-omics longitudinal study reveals alteration of the leukocyte activation pathway in COVID-19 patients
Severe coronavirus disease 2019 (COVID-19) infection may lead to lung injury, multi-organ
failure, and eventually death. Cytokine storm due to excess cytokine production has been …
failure, and eventually death. Cytokine storm due to excess cytokine production has been …
Comprehensive proteomics and meta-analysis of COVID-19 host response
H Babačić, W Christ, JE Araújo, G Mermelekas… - Nature …, 2023 - nature.com
COVID-19 is characterised by systemic immunological perturbations in the human body,
which can lead to multi-organ damage. Many of these processes are considered to be …
which can lead to multi-organ damage. Many of these processes are considered to be …