COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS …
MY Liu, B Zheng, Y Zhang, JP Li - Chronic Diseases and …, 2020 - mednexus.org
Coronavirus disease 2019 is a major threat to public health globally. Though its pathogenesis has not been fully elucidated, angiotensin-converting enzyme 2 (ACE2) has …
The emergence of SARS-CoV-2 has created an international health crisis, and small animal models mirroring SARS-CoV-2 human disease are essential for medical countermeasure …
COVID-19 causes more severe and frequently fatal disease in patients with pre-existing comorbidities such as hypertension and heart disease. SARS-CoV-2 virus enters host cells …
L Qu, C Chen, T Yin, Q Fang, Z Hong, R Zhou… - International journal of …, 2021 - mdpi.com
Despite the protracted battle against coronavirus acute respiratory infection (COVID-19) and the rapid evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
S Lei, S Wu - Combinatorial Chemistry & High Throughput …, 2023 - europepmc.org
Background Acute lung injury (ALI) is a serious lung disease characterized by acute and severe inflammation. Upregulation of ACE2 and inhibition of the NF-κB signaling pathway …
R Ye, Z Liu - Experimental and molecular pathology, 2020 - Elsevier
This study aimed to investigate the protective effect of angiotensin converting enzyme 2 (ACE2) on lipopolysaccharide (LPS)-induced acute lung injury (ALI). After generating ALI …
XC Pang, HX Zhang, Z Zhang, S Rinkiko, YM Cui… - Molecules, 2020 - mdpi.com
December 2019 saw the emergence of the coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which has spread …
CY Choi, J Villano, A Pekosz, H Jia - The Journal of Immunology, 2023 - journals.aai.org
Despite global efforts to end the pandemic of COVID19 which has claimed millions of lives in the past few years, there is no sign of the ending in foresee near future. One of the obstacles …