ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury

CH Lin - Physiology, 2024 - journals.physiology.org
The coronavirus disease 2019 (COVID-19) is a highly transmittable respiratory illness
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and acute lung …

[HTML][HTML] ACE2 and a Traditional Chinese Medicine Formula NRICM101 Could Alleviate the Inflammation and Pathogenic Process of Acute Lung Injury

CH Lin, YJ Chen, MW Lin, HJ Chang, XR Yang, CS Lin - Medicina, 2023 - mdpi.com
COVID-19 is a highly transmittable respiratory illness caused by SARS-CoV-2, and acute
lung injury (ALI) is the major complication of COVID-19. The challenge in studying SARS …

Role and mechanism of angiotensin-converting enzyme 2 in acute lung injury in coronavirus disease 2019

MY Liu, B Zheng, Y Zhang, JP Li - Chronic Diseases and …, 2020 - mednexus.org
Coronavirus disease 2019 is a major threat to public health globally. Though its
pathogenesis has not been fully elucidated, angiotensin-converting enzyme 2 (ACE2) has …

Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on acute lung injury in COVID-19

T Yamaguchi, M Hoshizaki, T Minato… - … for Annual Meeting of …, 2022 - researchgate.net
Angiotensin-converting enzyme 2 (ACE2) is a receptor for cell entry of SARS-CoV-2, and
recombinant soluble ACE2 protein inhibits SARS-CoV-2 infection as a decoy. ACE2 is a …

Lisinopril increases lung ACE2 levels and SARS-CoV-2 viral load and decreases inflammation but not disease severity in experimental COVID-19

Y Da Silva Santos, RL Pagni, TH Gamon… - Frontiers in … - frontiersin.org
COVID-19 causes more severe and frequently fatal disease in patients with pre-existing
comorbidities such as hypertension and heart disease. SARS-CoV-2 virus enters host cells …

[PDF][PDF] ACE2 can be a target for therapeutic purpose of COVID-19

M Khan, Z Cao, A Khan - Authorea Preprints, 2020 - techrxiv.org
Letter to editor It has been demonstrated that the latest outbreak-causing novel coronavirus
pneumonia (COVID-19) virus (2019-nCoV, SARS-CoV-2) invades human alveolar epithelial …

[HTML][HTML] Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

JW Golden, CR Cline, X Zeng, AR Garrison, BD Carey… - JCI insight, 2020 - ncbi.nlm.nih.gov
The emergence of SARS-CoV-2 has created an international health crisis, and small animal
models mirroring SARS-CoV-2 human disease are essential for medical countermeasure …

[HTML][HTML] Ace2 and innate immunity in the regulation of SARS-CoV-2-induced acute lung injury: A review

L Qu, C Chen, T Yin, Q Fang, Z Hong, R Zhou… - International journal of …, 2021 - mdpi.com
Despite the protracted battle against coronavirus acute respiratory infection (COVID-19) and
the rapid evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Zang Siwei Qingfei Mixture Alleviates Inflammatory Response to Attenuate Acute Lung Injury by the ACE2/NF-κB Signaling Pathway in Mice.

S Lei, S Wu - Combinatorial Chemistry & High Throughput …, 2023 - europepmc.org
Background Acute lung injury (ALI) is a serious lung disease characterized by acute and
severe inflammation. Upregulation of ACE2 and inhibition of the NF-κB signaling pathway …

ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway

R Ye, Z Liu - Experimental and molecular pathology, 2020 - Elsevier
This study aimed to investigate the protective effect of angiotensin converting enzyme 2
(ACE2) on lipopolysaccharide (LPS)-induced acute lung injury (ALI). After generating ALI …