Comparative analysis of ACE2 protein expression in rodent, non-human primate, and human respiratory tract at baseline and after injury: A conundrum for COVID-19 …

S Soni, Y Jiang, Y Tesfaigzi, JL Hornick, S Çataltepe - PLoS One, 2021 - journals.plos.org
Angiotensin converting enzyme 2 (ACE2) is the putative functional receptor for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Current literature on the abundance and …

Inhaled modified angiotensin converting enzyme 2 (ACE2) as a decoy to mitigate SARS-CoV-2 infection

R Ameratunga, K Lehnert, E Leung, D Comoletti… - 2020 - openaccess.wgtn.ac.nz
COVID-19 is a new zoonotic disease caused by the SARS-CoV-2 virus. Since its emergence
in Wuhan City, China, the virus has rapidly spread across the globe causing calamitous …

[HTML][HTML] Multifunctional angiotensin converting enzyme 2, the SARS-CoV-2 entry receptor, and critical appraisal of its role in acute lung injury

M Oz, DE Lorke - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a pandemic affecting
millions of individuals has raised great concern throughout the world, and the severe acute …

ACE2: its potential role and regulation in severe acute respiratory syndrome and COVID‐19

M Rezaei, SA Ziai, S Fakhri… - Journal of cellular …, 2021 - Wiley Online Library
COVID‐19, a new disease caused by the 2019‐novel coronavirus (SARS‐CoV‐2), has
swept the world and challenged its culture, economy, and health infrastructure. Forced …

Novel engineered recombinant ACE2 reduces SARS-CoV-2-induced COVID-19 without cardiotoxic side effects

F Ávila-Moreno - Molecular Therapy, 2024 - cell.com
In a recent issue of Molecular Therapy, 1 Song et al. describe an engineered human
angiotensin-converting enzyme 2 (ACE2), the entry receptor for severe acute respiratory …

The role and significance of angiotensin‐converting enzyme 2 peptides in the treatment of coronavirus disease 2019

Y Liu, H He, H Huang - Journal of Clinical Laboratory Analysis, 2021 - Wiley Online Library
Since the end of 2019, coronavirus disease 2019 (COVID‐19) caused by the novel
coronavirus (2019‐nCoV) posed a serious threat to human health and life. Therefore, the …

ACE2 in the era of SARS-CoV-2: controversies and novel perspectives

F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …

The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up‐Regulates Angiotensin‐Converting Enzyme 2 in …

JC Su, C Cheng, CY Wang, Y Zhang… - Evidence‐Based …, 2022 - Wiley Online Library
Xiaoqinglong decoction (XQLD), a classic prescription of Traditional Chinese Medicine, has
already been used clinically to cure acute lung injury (ALI), but its mechanism remains …

Angiotension converting enzyme 2 in the context of 2019 novel coronavirus infection: friend or foe?

JM Yang, X Meng, F Xue… - Zhonghua Xin Xue …, 2020 - pubmed.ncbi.nlm.nih.gov
2019 年 12 月, 湖北省武汉地区暴发新型冠状病毒 (2019-nCoV) 感染疫情. 由于 2019-nCoV
通过棘突糖蛋白与宿主呼吸道上皮细胞的血管紧张素转化酶 (ACE) 2 结合感染人体, ACE2 …

COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic mice

C Lutz, L Maher, C Lee, W Kang - Human Genomics, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a declared pandemic that is spreading all
over the world at a dreadfully fast rate. Severe acute respiratory syndrome coronavirus-2 …