The atlas of ACE2 expression in fetal and adult human hearts reveals the potential mechanism of heart-injured patients infected with SARS-CoV-2

X Shao, X Zhang, R Zhang, R Zhu… - … of Physiology-Cell …, 2022 - journals.physiology.org
Numerous studies have shown that severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) can infect host cells through binding to angiotensin I converting enzyme 2 (ACE2) …

Differential expression of ACE2 in the respiratory tracts and its relationship to COVID-19 pathogenesis

C Yang, Y Li, SY Xiao - EBioMedicine, 2020 - thelancet.com
Since its initial outbreak in December 2019 in Wuhan, China [1], COVID-19 has quickly and
firmly established itself as one of the most devastating global pandemics in history. Not only …

Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 …

SH Hammoud, Z Wehbe, S Abdelhady, F Kobeissy… - Molecular …, 2021 - ASPET
ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically
protective and virally conducive. The identification of ACE2 in as many as 72 tissues …

[PDF][PDF] Journal of Traditional Chinese Medical Sciences

A Jafarzadeh, S Jafarzadeh, M Nemati - pathogenesis, 2021 - canadahealthalliance.org
abstract In addition to the respiratory system, severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …

[HTML][HTML] Severe acute respiratory syndrome-coronavirus 2 infection: role of angiotensin-converting enzyme 2

J Shin - The Korean Journal of Medicine, 2020 - ekjm.org
A role of angiotensin-converting enzyme 2 (ACE2) in the coronavirus disease 2019
pandemic has been suggested, because it is the molecular receptor for severe acute …

Overview of pharmacotherapy targeting COVID-19 disease based on ACE-2: current challenges and future directions

A Vitiello, A Zovi, U Trama, F Ferrara - Herz, 2023 - Springer
The new Severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2) triggered the
pandemic of COVID-19, which is currently still ongoing. In 2021 a worldwide vaccine …

Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis

J Liu, Q Chen, S Liu, X Yang, Y Zhang, F Huang - Life sciences, 2018 - Elsevier
Aims Acute respiratory distress syndrome (ARDS), one of the serious form of acute lung
injury (ALI), is the primary cause of death in patients with ALI. Sini decoction (SND) is a …

[HTML][HTML] ACE2, much more than just a receptor for SARS-COV-2

L Samavati, BD Uhal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-
CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) …

A novel soluble ACE2 protein provides lung and kidney protection in mice susceptible to lethal SARS-CoV-2 infection

L Hassler, J Wysocki, I Gelarden, I Sharma… - Journal of the …, 2022 - journals.lww.com
Background Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) uses full-
length angiotensin converting enzyme 2 (ACE2) as a main receptor to enter target cells. The …

Role of ACE2-Ang (1–7)-Mas axis in post-COVID-19 complications and its dietary modulation

S Sahu, CR Patil, S Kumar, S Apparsundaram… - Molecular and Cellular …, 2022 - Springer
Severe acute respiratory syndrome-coronavirus-2 (COVID-19) virus uses Angiotensin-
Converting Enzyme 2 (ACE2) as a gateway for their entry into the human body. The ACE2 …