Toxoplasma gondii (T. gondii) is one of the most successful intracellular protozoan parasites
on earth and highly prevalent in most warm-blooded vertebrates. There are no drugs that …

Infection with the intracellular protozoan parasite Toxoplasma gondii causes serious public
health problems to both humans and livestock and of great economic impact worldwide …

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG-ODN) have
been characterized as Th1-promoting immunopotentiators, an adjuvant activity desirable for …

Bacterial DNA containing immunostimulatory motifs (CpG) induces the development of a
TH1 immune response. Since protection against Toxoplasma gondii is correlated with this …

To investigate the vaccine potential of multi-epitope vaccines against toxoplasmosis, a multi-
epitope DNA vaccine, eukaryotic plasmid pcDNA3. 1/T-ME expressing six antigen segments …

Abstract Aims To date, a Toxoplasma gondii vaccine for clinical use remains unavailable,
though multiple vaccine candidates have been suggested. In our previous studies …

Toxoplasma gondii is an apicomplexan parasite that affects both humans and livestock.
Transmitted to humans through ingestion, it is the second-leading cause of foodborne illness …

Toxoplasma gondii enters the mucosal surfaces of the host, and so immunity at these sites is
of major interest. Due to the compartmentalization of the immune response, systemic …

Protection against a challenge infection with Toxoplasma gondii VEG strain oocysts was
examined in pigs after vaccination with T. gondii RH strain tachyzoites with or without a …

There is no effective protective vaccine against human toxoplasmosis, which is a potential
threat to nearly a third of the world population. Vaccines based on virus-like particles (VLPs) …