Herein we investigated a new strategy for the modulation of cardiac macrophages to a
reparative state, at a predetermined time after myocardial infarction (MI), in aim to promote …

Macrophages are involved in every cardiovascular disease and are an attractive therapeutic
target. Macrophage activation is complex and can be either beneficial or deleterious …

Although reperfusion is essential in restoring circulation to ischemic myocardium, it also
leads to irreversible events including reperfusion injury, decreased cardiac function and …

Recent attempts at rebuilding the myocardium using stem cells have yielded disappointing
results. The lack of a supporting vasculature may, in part, explain these disappointing …

Aims To investigate whether activation of atheroprotective peritoneal B1a cells by apoptotic
cells or phosphatidylserine liposomes (PSLs) can enhance their protective actions during …

Adverse cardiac remodeling after myocardial infarction ultimately causes heart failure. To
stimulate reparative processes in the infarct, efficient delivery and retention of therapeutic …

Objectives. Selectins are important adhesion molecules which utilize a carbohydrate ligand
such as sialyl Lewisx (SLex). Our objective was to study the effects of a liposome-conjugated …

Background: After myocardial infarction, necrotic cardiomyocytes release damage-
associated proteins that stimulate innate immune pathways and macrophage tissue …

Exteriorized phosphatidylserine (PS) residues in apoptotic cells trigger rapid phagocytosis
by macrophage scavenger receptor pathways. Mimicking apoptosis with liposomes …

Macrophages have been suggested to be beneficial for myocardial wound healing. We
investigated the role of macrophages in myocardial wound healing by inhibition of …