Early transcriptional changes within liver, adrenal gland, and lymphoid tissues significantly contribute to ebola virus pathogenesis in cynomolgus macaques
Ebola virus (EBOV) continues to pose a significant threat to human health, as evidenced by
the 2013–2016 epidemic in West Africa and the ongoing outbreak in the Democratic …
the 2013–2016 epidemic in West Africa and the ongoing outbreak in the Democratic …
Distinct transcriptional responses to fatal Ebola virus infection in cynomolgus and rhesus macaques suggest species-specific immune responses
AN Pinski, KJ Maroney, A Marzi… - Emerging Microbes & …, 2021 - Taylor & Francis
Ebola virus (EBOV) is a negative single-stranded RNA virus within the Filoviridae family and
the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including …
the causative agent of Ebola virus disease (EVD). Nonhuman primates (NHPs), including …
[HTML][HTML] Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses
Ebola virus (EBOV) causes Ebola virus disease (EVD), marked by severe hemorrhagic
fever; however, the mechanisms underlying the disease remain unclear. To assess the …
fever; however, the mechanisms underlying the disease remain unclear. To assess the …
Ebola virus: new insights into disease aetiopathology and possible therapeutic interventions
TW Geisbert, LE Hensley - Expert reviews in molecular medicine, 2004 - cambridge.org
Ebola virus (EBOV) gained public notoriety in the last decade largely as a consequence of
the highly publicised isolation of a new EBOV species in a suburb of Washington, DC, in …
the highly publicised isolation of a new EBOV species in a suburb of Washington, DC, in …
Comparative transcriptomics highlights the role of the activator protein 1 transcription factor in the host response to ebolavirus
JW Wynne, S Todd, V Boyd, M Tachedjian… - Journal of …, 2017 - Am Soc Microbiol
Ebolavirus and Marburgvirus comprise two genera of negative-sense single-stranded RNA
viruses that cause severe hemorrhagic fevers in humans. Despite considerable research …
viruses that cause severe hemorrhagic fevers in humans. Despite considerable research …
Molecular mechanisms of Ebola pathogenesis
A Rivera, I Messaoudi - Journal of Leucocyte Biology, 2016 - academic.oup.com
Abstract Ebola viruses (EBOVs) and Marburg viruses (MARVs) are among the deadliest
human viruses, as highlighted by the recent and widespread Ebola virus outbreak in West …
human viruses, as highlighted by the recent and widespread Ebola virus outbreak in West …
Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes
J Kindrachuk, V Wahl-Jensen, D Safronetz… - Journal of …, 2014 - Am Soc Microbiol
Ebola virus (EBOV) causes a severe hemorrhagic disease in humans and nonhuman
primates, with a median case fatality rate of 78.4%. Although EBOV is considered a public …
primates, with a median case fatality rate of 78.4%. Although EBOV is considered a public …
The temporal program of peripheral blood gene expression in the response of nonhuman primates to Ebola hemorrhagic fever
KH Rubins, LE Hensley, V Wahl-Jensen… - Genome biology, 2007 - Springer
Abstract Background Infection with Ebola virus (EBOV) causes a fulminant and often fatal
hemorrhagic fever. In order to improve our understanding of EBOV pathogenesis and EBOV …
hemorrhagic fever. In order to improve our understanding of EBOV pathogenesis and EBOV …
Host factors in Ebola infection
AL Rasmussen - Annual review of genomics and human …, 2016 - annualreviews.org
Ebola virus (EBOV) emerged in West Africa in 2014 to devastating effect, and demonstrated
that infection can cause a broad range of severe disease manifestations. As the virus itself …
that infection can cause a broad range of severe disease manifestations. As the virus itself …
A conserved transcriptional response to intranasal Ebola virus exposure in nonhuman primates prior to onset of fever
E Speranza, SL Bixler, LA Altamura… - Science translational …, 2018 - science.org
Ebola virus disease (EVD), caused by Ebola virus (EBOV), is a severe illness characterized
by case fatality rates of up to 90%. The sporadic nature of outbreaks in resource-limited …
by case fatality rates of up to 90%. The sporadic nature of outbreaks in resource-limited …