Objective Early adolescence is a transition period during which many mental health
disorders emerge. The interplay between different internalizing and externalizing mental …

While research has linked alterations in functional connectivity of the default mode (DMN),
cognitive control (CCN), and salience networks (SN) to depression and anxiety, little …

Importance Many psychiatric disorders can be conceptualized as disorders of brain
maturation during childhood and adolescence. Discovering the neurobiological …

Background Early life adversity has been shown to affect outcomes at a later age, including
poorer cognitive function and increased risk for mental health disorders. The development of …

Background Early-life experiences have profound effects on functioning in adulthood.
Altered cortical development may be one mechanism through which early-life experiences …

Background Many mental disorders debut during adolescence, a period also involving
substantial brain development. The influence of environmental factors on child and …

Chronic conditions are common in childhood. We investigated the associations of childhood
chronic conditions reported by parents with subsequent self-reported internalizing and …

Background Adolescence is a period marked by heightened neural sensitivity to reward,
which is associated with less internalizing problems (Hanson et al., 2015; Ng et al., 2019) …

Background Internalizing disorders, such as anxiety and depressive disorders, are common
mental disorders in young people, but a detailed understanding of the symptom continuity …

Importance Adverse childhood experiences (ACEs) have been associated with poor mental
and physical health outcomes. However, the mechanism of this effect, critical to enhancing …