The single pill triple combination of aliskiren, amlodipine, and hydrochlorothiazide in the treatment of hypertension

Y Huan, R Townsend - Expert Opinion on Pharmacotherapy, 2012 - Taylor & Francis
Introduction: Hypertension is a leading cause of cardiovascular morbidity and mortality, and
uncontrolled hypertension remains common despite the availability of several classes of …

Aliskiren, amlodipine and hydrochlorothiazide triple combination for hypertension

E Judd, EA Jaimes - Expert review of cardiovascular therapy, 2012 - Taylor & Francis
Cardiovascular-related morbidity and mortality is linked to hypertension with proportional
gains in cardiovascular risk factor reduction with the lowering of blood pressure. Clinical trial …

Optimizing combination therapy in the management of hypertension: the role of the aliskiren, amlodipine, and hydrochlorothiazide fixed combination

MB Hovater, EA Jaimes - Integrated Blood Pressure Control, 2013 - Taylor & Francis
High blood pressure is the leading risk factor for death and disability worldwide, and the
prevalence is increasing. Effective treatment decreases the risk of adverse events in …

Safety and Efficacy of Aliskiren/Amlodipine/Hydrochlorothiazide Triple Combination in Patients With Moderate to Severe Hypertension: A 54‐Week, Open‐Label Study

AV Murray, W Koenig, J Garcia‐Puig… - The Journal of …, 2012 - Wiley Online Library
J Clin Hypertens (Greenwich). 2012; 14: 821–827.© 2012 Wiley Periodicals, Inc.
Combination antihypertensive therapies are recommended to attain blood pressure (BP) …

Clinic and ambulatory blood pressure lowering effect of aliskiren/amlodipine/hydrochlorothiazide combination in patients with moderate-to-severe hypertension: a …

Y Lacourcière, S Taddei, G Konis, H Fang… - Journal of …, 2012 - journals.lww.com
Objectives: To evaluate the clinic and ambulatory blood pressure (BP)-lowering efficacy and
safety of an aliskiren/amlodipine/hydrochlorothiazide (HCT) triple combination compared …

Fixed combinations in the pragmatic management of hypertension: focus on aliskiren and hydrochlorothiazide as a single pill

M Burnier - Integrated blood pressure control, 2010 - Taylor & Francis
A majority of hypertensive patients need more than one antihypertensive drug to control their
blood pressure. For this reason, most guidelines have introduced the possibility of …

Antihypertensive Efficacy and Tolerability of Aliskiren/Amlodipine Single-Pill Combinations in Patients with an Inadequate Response to Aliskiren Monotherapy¥

N Glorioso, M Thomas, C Troffa… - Current Vascular …, 2012 - ingentaconnect.com
Many patients with hypertension will require multiple antihypertensive drugs to achieve
blood pressure (BP) control. This double-blind study evaluated the efficacy and safety of …

Efficacy and safety of aliskiren and amlodipine combination therapy in patients with hypertension: a randomized, double-blind, multifactorial study

TW Littlejohn, SW Jones, J Zhang, H Hsu… - Journal of Human …, 2013 - nature.com
Most patients with hypertension need more than one drug to achieve blood pressure (BP)
control. This randomized, double-blind, multifactorial study evaluated whether combinations …

Aliskiren–hydrochlorothiazide combination for the treatment of hypertension

SG Chrysant - Expert Review of Cardiovascular Therapy, 2008 - Taylor & Francis
Hypertension is a major risk factor for cardiovascular morbidity and mortality and currently
has been estimated at 30% of the US population. Of these, only 36.8% have their blood …

Aliskiren/hydrochlorothiazide combination: in mild to moderate hypertension

CM Baldwin, GL Plosker - Drugs, 2009 - Springer
Abstract▲ Aliskiren/hydrochlorothiazide is a single-pill combination of the first in the new
class of non-peptide direct renin inhibitors (aliskiren) and a thiazide diuretic …