Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection
R Littera, L Chessa, S Deidda, G Angioni… - PloS One, 2021 - journals.plos.org
Background The diversity in the clinical course of COVID-19 has been related to differences
in innate and adaptative immune response mechanisms. Natural killer (NK) lymphocytes are …
in innate and adaptative immune response mechanisms. Natural killer (NK) lymphocytes are …
[HTML][HTML] SARS-CoV-2 peptides bind to NKG2D and increase NK cell activity
H Kim, JE Byun, SR Yoon, H Koohy, H Jung, I Choi - Cellular immunology, 2022 - Elsevier
Immune dysregulation is commonly observed in patients with coronavirus disease 2019
(COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces …
(COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces …
Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease
M Li, W Guo, Y Dong, X Wang, D Dai, X Liu… - Frontiers in …, 2020 - frontiersin.org
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induced
Coronavirus Disease 2019 (COVID-19) has posed a global threat to public health. The …
Coronavirus Disease 2019 (COVID-19) has posed a global threat to public health. The …
Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention
Background New COVID-19 treatments are desperately needed as case numbers continue
to rise and emergent strains threaten vaccine efficacy. Cell therapy has revolutionized …
to rise and emergent strains threaten vaccine efficacy. Cell therapy has revolutionized …
Coordinated Loss and Acquisition of NK Cell Surface Markers Accompanied by Generalized Cytokine Dysregulation in COVID-19
MO Ustiuzhanina, JD Vavilova, AA Boyko… - International Journal of …, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, is accompanied
by a dysregulated immune response. In particular, NK cells, involved in the antiviral …
by a dysregulated immune response. In particular, NK cells, involved in the antiviral …
[HTML][HTML] Fatal COVID-19 infections: Is NK cell dysfunction a link with autoimmune HLH?
MS Osman, C van Eeden, JWC Tervaert - Autoimmunity Reviews, 2020 - ncbi.nlm.nih.gov
Shoenfeld [1] postulates that in COVID-19 infected patients a clinical constellation of
cytokine storm, respiratory failure and eventually death is reminiscent of a “hyperferritinemic …
cytokine storm, respiratory failure and eventually death is reminiscent of a “hyperferritinemic …
Major reduction of NKT cells in patients with severe COVID-19 pneumonia
MA Zingaropoli, V Perri, P Pasculli, FC Dezza… - Clinical …, 2021 - Elsevier
Background NK cells seem to be mainly involved in COVID-19 pneumonia. Little is known
about NKT cells which represent a bridge between innate and adaptive immunity. Methods …
about NKT cells which represent a bridge between innate and adaptive immunity. Methods …
Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models
H Lu, Z Liu, X Deng, S Chen, R Zhou, R Zhao… - PLoS …, 2023 - journals.plos.org
One of the major pathogenesis mechanisms of SARS-CoV-2 is its potent suppression of
innate immunity, including blocking the production of type I interferons. However, it is …
innate immunity, including blocking the production of type I interferons. However, it is …
NK cell receptor and ligand composition influences the clearance of SARS-CoV-2
WC Hsieh, EY Lai, YT Liu, YF Wang… - The Journal of …, 2021 - Am Soc Clin Investig
To explore how the immune system controls clearance of SARS-CoV-2, we used a single-
cell, mass cytometry–based proteomics platform to profile the immune systems of 21 patients …
cell, mass cytometry–based proteomics platform to profile the immune systems of 21 patients …
Natural killer cell responses to emerging viruses of zoonotic origin
C Diaz-Salazar, JC Sun - Current opinion in virology, 2020 - Elsevier
Highlights•Emerging viruses avoid immune recognition by dampening early pro-
inflammatory responses.•Natural hosts of zoonotic viruses have developed enhanced …
inflammatory responses.•Natural hosts of zoonotic viruses have developed enhanced …