The mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase 1/2
(ERK1/2) signaling pathway is widely activated by a variety of extracellular stimuli, and its …

The extracellular signal regulated kinase (ERK1 and ERK2) signal transduction pathways
play a critical role in cell proliferation. Hyperactivation of the ERK proteins either through …

Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein
kinase family of signaling molecules. ERK is predominantly found in two forms, ERK1 (p44) …

Signaling through the AKT and ERK pathways controls cell proliferation. However, the
integrated regulation of this multistep process, involving signal processing, cell growth and …

The rapid phosphorylation and dephosphorylation of a variety of proteins downstream of the
endothelin receptors A and B was investigated following stimulation of human lung …

The Tec kinases represent the second largest family of mammalian non-receptor tyrosine
kinases and are distinguished by the presence of distinct proline-rich regions and pleckstrin …

Abstract eps8, a recently identified tyrosine kinase substrate, has been shown to augment
epidermal growth factor (EGF) responsiveness, implicating it in EGF receptor (EGFR) …

Eukaryotic initiation factor 2 alpha kinases (eIF-2α kinases) are key mediators of stress
response in cells. In mammalian cells, there are four eIF-2α kinases, namely HRI (Heme …

Epidermal growth factor (EGF) and its receptor (EGFR) have been shown to play a
significant role in the pathogenesis of glioblastoma. In our study, the EGFR was stimulated …

This review point out several aspects regarding the mitogen‐activated protein kinase
(MAPK)/extracellular‐regulated kinase (Erk) network, which are still pending issues in the …