Clinicians have long recognized the syndromic association between Wilms tumor and a
variety of genetic disorders. The recent identification of molecular mechanisms associated …

Wilms tumour has been reported in association with over 50 different clinical conditions and
several abnormal constitutional karyotypes. Conclusive evidence of an increased risk of …

The Oncology Grand Rounds series is designed to place original reports published in the
Journal into clinical context. A case presentation is followed by a description of diagnostic …

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Abstract Wilms' tumor (WT), the most common childhood kidney cancer, develops in
association with an underlying germline predisposition in up to 15% of cases. Germline …

Abstract Background Wilms Tumor (WT) can occur in association with tumor predisposition
syndromes and/or with clinical malformations. These associations have not been fully …

Somatic defects at five loci, WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region, are
implicated in Wilms tumor, the commonest childhood kidney cancer. In this study we …

Wilms' tumour (WT; nephroblastoma), a kidney neoplasm, is one of the most frequently
occurring solid tumours of childhood. It arises from the developing kidney by genetic and …

Wilms tumor can occur in association with a number of recognizable patterns of
malformation, as first described by Miller et al. in 1964 [1]. This paper represents a synthesis …

The past decade has witnessed substantial growth in our knowledge of the genes and loci
that are altered in Wilms tumor. Although Wilms tumor was one of the original paradigms of …