Most organs in the body rely on blood flow, and vesicular damage is the leading cause of
injury in multiple organs. The endothelium, as the barriers of vessels, play a critical role in …

Atherosclerosis is a significant cardiovascular burden and a leading cause of death
worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel …

Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Pyroptosis, a newly discovered form of programmed cell death, is characterized by cell
swelling, the protrusion of large bubbles from the plasma membrane and cell lysis. This …

Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin D (GSDMD)-mediated membrane pore formation, cell swelling and rapid lysis …

Programmed cell deaths are pathways involving cells playing an active role in their own
destruction. Depending on the signaling system of the process, programmed cell death can …

Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by
gasdermin protein-mediated membrane pore formation, cell swelling, and rapid lysis …

Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

Cell death and inflammation are the fundamental biological processes in both normal
physiology and pathology. Apoptosis is the most well-studied process of cell death, but there …

Programmed cell death (PCD) is regarded as a pathological form of cell death with an
intracellular program mediated, which plays a pivotal role in maintaining homeostasis and …