RNA viruses are responsible for some of the worst pandemics known to mankind, including
outbreaks of Influenza, Ebola, and COVID-19. One major challenge in tackling RNA viruses …

Populations of RNA viruses are often characterized by abundant genetic variation. However,
the relative fitness of these mutations is largely unknown, although this information is central …

RNA viruses are often thought of as possessing almost limitless adaptability as a result of
their extreme mutation rates. However, high mutation rates also put a cap on the size of the …

Gene overlapping is widely employed by RNA viruses to generate genetic novelty while
retaining a small genome size. However, gene overlapping also increases the deleterious …

RNA viruses exist as genetically diverse populations. It is thought that diversity and genetic
structure of viral populations determine the rapid adaptation observed in RNA viruses and …

RNA viruses are the main agents of emerging and re-emerging diseases. It is therefore
important to reveal the evolutionary processes that underpin their ability to jump species …

RNA viruses are the main agents of emerging disease. To understand how RNA viruses are
able to jump species boundaries and spread in new hosts it is essential to determine the …

The replication machinery of most RNA viruses lacks proofreading mechanisms. As a result,
RNA virus populations harbor a large amount of genetic diversity that confers them the …

The increasing availability of complete genome sequences of RNA viruses has the potential
to shed new light on fundamental aspects of their biology. Here, I use case studies of 3 RNA …

RNA viruses are notorious for rapidly generating genetically diverse populations during a
single replication cycle, and the implications of this mutant population, often referred to as …