Anti-SARS-CoV-2 antibodies within IVIg preparations: cross-reactivities with seasonal coronaviruses, natural autoimmunity, and therapeutic implications

MC Dalakas, K Bitzogli, H Alexopoulos - Frontiers in immunology, 2021 - frontiersin.org
Introduction: Cross-reactivity to SARS-CoV-2 antigenic peptides has been detected on T-
cells from pre-pandemic donors due to recognition of conserved protein fragments within …

Interferon gamma immunotherapy in five critically ill COVID-19 patients with impaired cellular immunity: A case series

A van Laarhoven, L Kurver, GJ Overheul, EJ Kooistra… - Med, 2021 - cell.com
Background Prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
shedding has been described in immunocompromised coronavirus disease 2019 (COVID …

Immunotherapies for COVID-19: lessons learned from sepsis

KE Remy, SC Brakenridge, B Francois… - The Lancet …, 2020 - thelancet.com
Therapeutic approaches to mitigate the severe acute lung injury associated with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have rapidly entered …

[PDF][PDF] Plasma from post-COVID-19 and COVID-19-vaccinated donors results in highly potent SARS-CoV-2 neutralization by intravenous immunoglobulins

M Karbiener, MR Farcet, J Schwaiger, N Powers… - J Infect Dis, 2021 - researchgate.net
A rapidly increasing proportion of the US population, including plasma donors, now carries
SARS-CoV-2 neutralizing antibodies, a consequence of earlier COVID-19 or–for many more …

Immunotherapy for SARS-CoV-2: potential opportunities

M Pashaei, N Rezaei - Expert opinion on biological therapy, 2020 - Taylor & Francis
Coronavirus Disease 2019 (COVID-19), caused by a novel coronavirus, called Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), emerged at the end of 2019 in Wuhan …

Neutralizing autoantibodies to type I interferons in COVID-19 convalescent donor plasma

SE Vazquez, P Bastard, K Kelly, A Gervais… - Journal of clinical …, 2021 - Springer
Convalescent plasma has been a mainstay therapeutic in passive immunization for
decades. In the setting of the novel coronavirus (SARS-CoV-2), it has become widely used …

[HTML][HTML] Adjunct immunotherapies for the management of severely ill COVID-19 patients

SR Bonam, SV Kaveri, A Sakuntabhai, L Gilardin… - Cell Reports …, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). It has infected millions, with more than 275,000 fatal cases as …

Passive antibody therapy in COVID-19

J Abraham - Nature Reviews Immunology, 2020 - nature.com
For over a century, transfusion of convalescent plasma from recovered individuals has been
tried as a therapeutic approach when a novel pathogen emerges. As the world awaits SARS …

Immunotherapy for COVID-19: Evolving treatment of viral infection and associated adverse immunological reactions

JS Putter - Transfusion and Apheresis Science, 2021 - Elsevier
This review on COVID-19 immunotherapy enables a comparative analysis of the short-list of
currently approved major vaccines. These include the Pfizer and Moderna first mRNA …

COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2)

Y Song, M Zhang, L Yin, K Wang, Y Zhou… - International journal of …, 2020 - Elsevier
Currently, there is no approved therapy for coronavirus disease 2019 (COVID-19). The
World Health Organization (WHO) therefore endorses supportive care only. However …