Inflammatory bowel diseases are characterized by disabilities in gastrointestinal system and
defects in mucosal immune system. Statins are 3-hydroxy-3-methyl glutaryl coenzyme A …

Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce
inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in …

Inflammatory bowel diseases (IBD) with chronic infiltration of immune cells in the
gastrointestinal tract are common and largely incurable. The therapeutic targeting of IBD has …

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and there is no specific drug to treat it. Recent results showed that 17-beta …

Inflammatory bowel disease (IBD) is an umbrella term for the chronic immune-mediated
idiopathic inflammation of the gastrointestinal tract, manifesting as Crohn's disease (CD) or …

Introduction Hyporesponsiveness of human lamina propria immune cells to microbial and
nutritional antigens represents one important feature of intestinal homeostasis. It is at least …

Cholesterol is a multifaceted metabolite that is known to modulate processes in cancer,
atherosclerosis, and autoimmunity. A common denominator between these diseases …

The nuclear receptor peroxisome proliferator-activated receptors (PPARs) are important in
regulating lipid metabolism and inflammatory responses in macrophages. Activation of …

Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disease that affects the
large intestine and exhibits a relapsing and remitting course. It is a complex immune …

B10 cells are regulatory B cells capable of producing IL-10 for maintaining immune
homeostasis. Dysregulation of B10 cells occurs in autoimmune and inflammatory diseases …