Novel SARS-CoV-2/COVID-19: Origin, pathogenesis, genes and genetic variations, immune responses and phylogenetic analysis

Y Junejo, M Ozaslan, M Safdar, RA Khailany… - Gene reports, 2020 - Elsevier
In this review, we focused on the origins of the novel coronavirus (SARS-CoV-2), origin,
pathogenesis, immune responses, genes and genetic variations, phylogenetic analyses …

[HTML][HTML] Immunological aspects of COVID-19: What do we know?

TV Velikova, SV Kotsev, DS Georgiev… - World Journal of …, 2020 - ncbi.nlm.nih.gov
The newly emerged coronavirus (severe acute respiratory syndrome coronavirus 2 SARS-
CoV-2) and the disease that it causes coronavirus disease 2019 (COVID-19) have changed …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

Dysregulation of cell signaling by SARS-CoV-2

RK Suryawanshi, R Koganti, A Agelidis, CD Patil… - Trends in …, 2021 - cell.com
Pathogens usurp host pathways to generate a permissive environment for their propagation.
The current spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

[HTML][HTML] Molecular immune pathogenesis and diagnosis of COVID-19

X Li, M Geng, Y Peng, L Meng, S Lu - Journal of pharmaceutical analysis, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of …

SARS-CoV-2 and COVID-19: from the bench to the bedside

S Romagnoli, A Peris, AR De Gaudio… - Physiological …, 2020 - journals.physiology.org
First isolated in China in early 2020, Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) is the novel coronavirus responsible for the ongoing pandemic of …

[HTML][HTML] Recent understandings toward coronavirus disease 2019 (COVID-19): from bench to bedside

J Yu, P Chai, S Ge, X Fan - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
In late December 2019, an unprecedented outbreak of coronavirus disease 2019 (COVID-
19) caused by SARS coronavirus 2 (SARS-CoV-2)(previously named 2019-nCoV) in Wuhan …

[HTML][HTML] COVID-19 pandemic: from molecular biology, pathogenesis, detection, and treatment to global societal impact

S Sood, V Aggarwal, D Aggarwal, SK Upadhyay… - Current pharmacology …, 2020 - Springer
Abstract Purpose of Review In December 2019, there was an outbreak of viral disease in
Wuhan, China which raised the concern across the whole world. The viral disease caused …

Pathogenesis of COVID-19 from a cell biology perspective

RJ Mason - European Respiratory Journal, 2020 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) is a major health concern and can be devastating,
especially for the elderly. COVID-19 is the disease caused by the SARS-CoV-2 virus …

[HTML][HTML] Severe COVID-19 patients show an increase in soluble TNFR1 and ADAM17, with a relationship to mortality

Y Palacios, A Ruiz, LA Ramón-Luing… - International journal of …, 2021 - mdpi.com
Overproduction of inflammatory cytokines is a keystone event in COVID-19 pathogenesis;
TNF and its receptors (TNFR1 and TNFR2) are critical pro-inflammatory molecules. ADAM17 …