Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in
humans more than two years ago and caused an unprecedented socio-economic burden on …

First isolated in China in early 2020, Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) is the novel coronavirus responsible for the ongoing pandemic of …

Overproduction of inflammatory cytokines is a keystone event in COVID-19 pathogenesis;
TNF and its receptors (TNFR1 and TNFR2) are critical pro-inflammatory molecules. ADAM17 …

Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by lung injury,
cytokine storm, and increased neutrophil-to-lymphocyte ratio (NLR). Current therapies focus …

The drivers of critical coronavirus disease 2019 (COVID-19) remain unknown. Given major
confounding factors such as age and comorbidities, true mediators of this condition have …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …

Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

COVID-19 has emerged as a global pandemic. It is mainly manifested as pneumonia which
may deteriorate into severe respiratory failure. The major hallmark of the disease is the …

The severe‐acute‐respiratory‐syndrome‐coronavirus‐2 (SARS‐CoV‐2) is the causative
agent of COVID‐19, but host cell factors contributing to COVID‐19 pathogenesis remain only …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to
respiratory illness and multi-organ failure in critically ill patients. Although the virus-induced …