Numerous studies on the biological mechanism of breast cancer have identified a number of
potential therapeutic molecular targets. In this context, one type of potential candidates …

The actin cytoskeleton plays an important role in various cellular processes. The different
forms ofactin (G-actin and F-actin) participate in the organization of nuclear structure and its …

We have previously demonstrated that carnosol, a naturally occurring diterpene, inhibited in
vitro cell viability and colony growth, as well as induced cell cycle arrest, autophagy and …

Annexin A1 (AnxA1) is a pleiotropic protein that exerts essential roles in breast cancer (BC)
growth and aggressiveness. In our previous work, we described the autocrine signaling of …

Hispolon has been shown to have anticancer effects on various tumors. However, whether
hispolon exerts anti-migration activity in breast cancer cells and the underlying mechanisms …

AP-2 proteins are a family of developmentally-regulated transcription factors. They are
encoded by five different genes (α, β, γ, δ, and ε) but they share a common structure. AP-2 …

Abstracts Previous studies report the upregulation of the secretory Rab27B small GTPase in
human breast cancer, which could promote invasive growth and metastasis in estrogen …

Background/Aims: Calycosin, a phytoestrogenic compound, has recently emerged as a
promising antitumor drug. It has been shown that calycosin suppresses growth and induces …

Metastasis is the leading cause of death in breast cancer patients. Osthole, as an active
compound detected in the traditional Chinese medicine Wenshen Zhuanggu Formula, has …

Abstract Profilin1 (Pfn1) functions as a tumour suppressor against malignant phenotypes of
cancer cells. A minimum level of Pfn1 is critical for the differentiation of human epithelial …