Analysis of the microbiome: Advantages of whole genome shotgun versus 16S amplicon sequencing
The human microbiome has emerged as a major player in regulating human health and
disease. Translational studies of the microbiome have the potential to indicate clinical …
disease. Translational studies of the microbiome have the potential to indicate clinical …
Comparing apples and oranges?: next generation sequencing and its impact on microbiome analysis
Rapid advancements in sequencing technologies along with falling costs present
widespread opportunities for microbiome studies across a vast and diverse array of …
widespread opportunities for microbiome studies across a vast and diverse array of …
Shallow shotgun sequencing reduces technical variation in microbiome analysis
AJ La Reau, NB Strom, E Filvaroff, K Mavrommatis… - Scientific reports, 2023 - nature.com
The microbiome is known to play a role in many human diseases, but identifying key
microbes and their functions generally requires large studies due to the vast number of …
microbes and their functions generally requires large studies due to the vast number of …
Quantitative assessment of shotgun metagenomics and 16S rDNA amplicon sequencing in the study of human gut microbiome
I Laudadio, V Fulci, F Palone, L Stronati… - OMICS: A Journal of …, 2018 - liebertpub.com
The analysis of microbiota composition in humans, animals, and built environments is
important because of emerging roles and applications in a broad range of disease and …
important because of emerging roles and applications in a broad range of disease and …
An introduction to next generation sequencing bioinformatic analysis in gut microbiome studies
The gut microbiome is a microbial ecosystem which expresses 100 times more genes than
the human host and plays an essential role in human health and disease pathogenesis …
the human host and plays an essential role in human health and disease pathogenesis …
Gut microbiome diversity detected by high-coverage 16S and shotgun sequencing of paired stool and colon sample
J Mas-Lloret, M Obón-Santacana, G Ibáñez-Sanz… - Scientific data, 2020 - nature.com
The gut microbiome has a fundamental role in human health and disease. However,
studying the complex structure and function of the gut microbiome using next generation …
studying the complex structure and function of the gut microbiome using next generation …
Progress of analytical tools and techniques for human gut microbiome research
Massive DNA sequencing studies have expanded our insights and understanding of the
ecological and functional characteristics of the gut microbiome. Advanced sequencing …
ecological and functional characteristics of the gut microbiome. Advanced sequencing …
Characterization of shallow whole-metagenome shotgun sequencing as a high-accuracy and low-cost method by complicated mock microbiomes
W Xu, T Chen, Y Pei, H Guo, Z Li, Y Yang… - Frontiers in …, 2021 - frontiersin.org
Characterization of the bacterial composition and functional repertoires of microbiome
samples is the most common application of metagenomics. Although deep whole …
samples is the most common application of metagenomics. Although deep whole …
High throughput sequencing methods and analysis for microbiome research
High-throughput sequencing technology is rapidly improving in quality, speed and cost. It is
therefore becoming more widely used to study whole communities of prokaryotes in many …
therefore becoming more widely used to study whole communities of prokaryotes in many …
Library preparation methodology can influence genomic and functional predictions in human microbiome research
MB Jones, SK Highlander… - Proceedings of the …, 2015 - National Acad Sciences
Observations from human microbiome studies are often conflicting or inconclusive. Many
factors likely contribute to these issues including small cohort sizes, sample collection, and …
factors likely contribute to these issues including small cohort sizes, sample collection, and …