511. Treatment with molnupiravir in the MOVe-in and MOVe-out clinical trials results in an increase in transition mutations across the SARS-CoV-2 genome

J Strizki, J Grobler, Y Zhang, J Du… - Open Forum …, 2021 - academic.oup.com
Background COVID-19 has been an unprecedented pandemic resulting in high mortality.
We report our experience of using a treatment protocol in the intensive care unit (ICU) during …

Estimation of COVID-19 burden in Egypt–Authors' reply

AR Tuite, V Ng, E Rees, D Fisman… - The Lancet Infectious …, 2020 - thelancet.com
1 Tuite AR, Ng V, Rees E, et al. Estimation of the COVID-19 burden in Egypt through
exported case detection. Lancet Infect Dis 2020; published online March 26. https://doi …

Characteristics and outcomes of US Veterans at least 65 years of age at high risk of severe SARS-CoV-2 infection with or without receipt of oral antiviral agents

CA Gentry, P Nguyen, SK Thind, G Kurdgelashvili… - Journal of infection, 2023 - Elsevier
Objectives Molnupiravir and nirmatrelvir/ritonavir each became available in the United
States (US) through the Food and Drug Administration (FDA) emergency use authorization …

Cellular immunity against SARS-CoV-2 depends on the serological status

L Pighi, BM Henry, S De Nitto… - Journal of …, 2023 - journalofinfection.com
Cellular and humoral immunity against severe acute respiratory syndrome coronavirus
(SARS-CoV-2), either naturally acquired or vaccine-elicited, are both essential for limiting …

Temporal changes in SARS-CoV-2 clearance kinetics and the optimal design of antiviral pharmacodynamic studies: an individual patient data meta-analysis of a …

P Wongnak, WHK Schilling, P Jittamala… - The Lancet Infectious …, 2024 - thelancet.com
Background Effective antiviral drugs prevent hospitalisation and death from COVID-19.
Antiviral efficacy can be efficiently assessed in vivo by measuring rates of SARS-CoV-2 …

Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection

AT Hanrath, BAI Payne, CJA Duncan - Journal of Infection, 2021 - journalofinfection.com
It has been recently suggested that prior exposure to seasonal coronaviruses might confer
cross-protection against SARS-CoV-2. 1 Whether SARS-CoV-2 infection itself confers …

[HTML][HTML] Molnupiravir for intra-household prevention of COVID-19: the MOVe-AHEAD randomized, placebo-controlled trial

SA Alpizar, J Accini, DC Anderson, B Eysa… - Journal of Infection, 2023 - Elsevier
Objectives To evaluate the efficacy and safety of molnupiravir for intra-household post-
exposure prophylaxis (PEP) of COVID-19. Methods MOVe-AHEAD was a randomized …

SARS-CoV-2 shedding and infectivity–Authors' reply

F Zhou, G Fan, Z Liu, B Cao - Lancet (London, England), 2020 - ncbi.nlm.nih.gov
1 Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients
with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395: 1054–62. 2 …

[PDF][PDF] Effectiveness of mRNA-based vaccines during the emergence of SARS-CoV-2 Omicron variant

A Sharma, G Oda, M Holodniy - Clinical Infectious Diseases: An …, 2022 - scholar.archive.org
Abstract 1 Background 2 We evaluated effectiveness of mRNA-based vaccines following
emergence of SARS-CoV-2 3 Omicron variant. 4 Methods 5 Recipients of a third dose of …

COVID-19: find the right questions to be answered

A Giacomelli, S Antinori, A Gori… - Clinical Infectious …, 2024 - academic.oup.com
TO THE EDITOR—We read with great interest the article by Montejano and colleagues,
which aimed to assess how the inclusion criteria of ongoing phase 2 and 3 clinical trials for …