Triphenyl phosphate‐induced macrophages dysfunction by activation TLR4‐mediated ERK/NF‐κB pathway
Z Lin, W Zhang, X Li, B Du, T Li, H He… - Environmental …, 2023 - Wiley Online Library
Triphenyl phosphate (TPHP) is one of the most widely used organic phosphorus flame
retardants and is ubiquitous in the environment. Studies have been reported that TPHP may …
retardants and is ubiquitous in the environment. Studies have been reported that TPHP may …
[HTML][HTML] Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice
C Peng, X Zhang, Y Chen, L Wang - Ecotoxicology and Environmental …, 2023 - Elsevier
Triphenyl phosphate (TPHP), one widely used organophosphate flame retardant, has
attracted accumulating attention due to its high detection rate in human biological samples …
attracted accumulating attention due to its high detection rate in human biological samples …
In vitro immunotoxicity of organophosphate flame retardants in human THP-1-derived macrophages
X Li, N Li, K Rao, Q Huang, M Ma - Environmental Science & …, 2020 - ACS Publications
Scarce attention has been paid to the immunotoxicity of organophosphate flame retardants
(PFRs), which poses a challenge to the systematic assessment of their health risks. In this …
(PFRs), which poses a challenge to the systematic assessment of their health risks. In this …
[HTML][HTML] Lipid metabolic disturbance induced by triphenyl phosphate and hydroxy metabolite in HepG2 cells
J An, J Jiang, W Tang, Y Zhong, G Ren… - Ecotoxicology and …, 2023 - Elsevier
Triphenyl phosphate (TPHP) has been widely used as flame retardants and been detected
with increasing frequency in environment. TPHP can transform into mono-hydroxylated …
with increasing frequency in environment. TPHP can transform into mono-hydroxylated …
Endoplasmic reticulum stress participates in apoptosis of HeLa cells exposed to TPHP and OH-TPHP via the eIF2α-ATF4/ATF3-CHOP-DR5/P53 signaling pathway
J An, C Du, W Xue, J Huang, Y Zhong… - Toxicology …, 2023 - academic.oup.com
Purpose Triphenyl phosphate (TPHP) is a widely used organophosphate flame retardant,
which can be transformed in vivo into diphenyl phosphate (DPHP) and 4-hydroxyphenyl …
which can be transformed in vivo into diphenyl phosphate (DPHP) and 4-hydroxyphenyl …
Pipoxolan suppresses the inflammatory factors of NF‐κB, AP‐1, and STATs, but activates the antioxidative factor Nrf2 in LPS‐stimulated RAW 264.7 murine …
YH Lin, YJ Lin, TH Chang, YH Chang… - Environmental …, 2020 - Wiley Online Library
Although pipoxolan (PIPO) is a smooth muscle relaxant, its anti‐inflammatory capability has
not been studied. Therefore, we investigated the anti‐inflammatory molecular mechanisms …
not been studied. Therefore, we investigated the anti‐inflammatory molecular mechanisms …
[HTML][HTML] Triphenyl phosphate exposure induces kidney structural damage and gut microbiota disorders in mice under different diets
H Cui, Y Chang, X Jiang, M Li - Environment International, 2020 - Elsevier
Exposure of humans to organophosphate flame retardants (OPFRs) and the consequent
health risk have increased owing to the latter's widespread application. Although triphenyl …
health risk have increased owing to the latter's widespread application. Although triphenyl …
Triphenyl phosphate induces cardiotoxicity through myocardial fibrosis mediated by apoptosis and mitophagy of cardiomyocyte in mice
F Xu, Y He, A Xu, L Ren, J Xu, Y Shao, M Wang… - Environmental …, 2024 - Elsevier
Triphenyl phosphate (TPHP) is an organophosphorus flame retardant, but its cardiac toxicity
has not been adequately investigated. Therefore, in the current study, the effect of TPHP on …
has not been adequately investigated. Therefore, in the current study, the effect of TPHP on …
The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264. 7 cells
HR Kim, KH Chung - Toxicology letters, 2015 - Elsevier
Polyhexamethylene guanidine (PHMG) phosphate is a competitive disinfectant with strong
antibacterial activity. However, epidemiologists revealed that inhaled PHMG-phosphate may …
antibacterial activity. However, epidemiologists revealed that inhaled PHMG-phosphate may …
Triphenyl phosphate disturbs the lipidome and induces endoplasmic reticulum stress and apoptosis in JEG-3 cells
Y Wang, J Hong, M Shi, L Guo, L Liu, H Tang, X Liu - Chemosphere, 2021 - Elsevier
Triphenyl phosphate (TPP) is a frequently used aryl organophosphate flame retardant.
Epidemiological studies have shown that TPP and its metabolite diphenyl phosphate (DPP) …
Epidemiological studies have shown that TPP and its metabolite diphenyl phosphate (DPP) …