Importance Genome-wide investigations provide systematic information regarding the
neurobiology of psychiatric disorders. Objective To identify biological pathways that …

Schizophrenia and bipolar disorder are serious mental illnesses that affect more than 2% of
adults. While large-scale genetics studies have identified genomic regions associated with …

Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …

Bipolar disorder (BD) is a highly heritable neuropsychiatric disease characterized by
recurrent episodes of mania and depression. BD shows substantial clinical and genetic …

Ten years ago it was widely expected that the genetic basis of common disease would be
resolved by genome-wide association studies (GWAS), large-scale studies in which the …

We examined the role of common genetic variation in schizophrenia in a genome-wide
association study of substantial size: a stage 1 discovery sample of 21,856 individuals of …

Recently, genome-wide association studies (GWAS) have yielded replicable findings and
confirmed previous candidate genes as important factors in non-psychiatric diseases such …

An overall burden of rare structural genomic variants has not been reported in bipolar
disorder (BD), although there have been reports of cases with microduplication and …

We have conducted a genotyping study using a custom Illumina Infinium HD genotyping
array, the ImmunoChip, in a new UK sample of 1218 bipolar disorder (BD) cases and 2913 …

Given the mounting convergent evidence implicating many more genes in complex
disorders such as bipolar disorder than the small number identified unambiguously by the …