Nitric oxide deficiency in chronic kidney disease

C Baylis - American Journal of Physiology-Renal …, 2008 - journals.physiology.org
The overall production of nitric oxide (NO) is decreased in chronic kidney disease (CKD)
which contributes to cardiovascular events and further progression of kidney damage. There …

Arginine, arginine analogs and nitric oxide production in chronic kidney disease

C Baylis - Nature Clinical Practice Nephrology, 2006 - nature.com
Nitric oxide (NO) production is reduced in renal disease, partially due to decreased
endothelial NO production. Evidence indicates that NO deficiency contributes to …

[HTML][HTML] Total nitric oxide production is low in patients with chronic renal disease

RJ Schmidt, C Baylis - Kidney international, 2000 - Elsevier
Total nitric oxide production is low in patients with chronic renal disease. Background A
deficiency of the endogenous vasodilator nitric oxide (NO) has been implicated as a …

The endothelium as a target in renal diseases.

C Zoccali - Journal of nephrology, 2007 - europepmc.org
The endothelium is a fundamental layer in the arterial wall both for the local regulation of
flow to critical organs like the heart, brain and kidney, and for the protection of the vascular …

Indices of activity of the nitric oxide system in hemodialysis patients

RJ Schmidt, J Domico, LS Samsell, S Yokota… - American journal of …, 1999 - Elsevier
Arginine deficiency and/or increased levels of circulating nitric oxide (NO) synthesis (NOS)
inhibitors can cause reduced NOS, which may contribute to hypertension in patients with …

Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study

D Fliser, F Kronenberg, JT Kielstein… - Journal of the …, 2005 - journals.lww.com
Reduced bioavailability of nitric oxide (NO) is thought to play an important role in
progression of renal damage. The hypothesis that the endogenous NO synthase inhibitor …

Nitric oxide, oxidative stress, and progression of chronic renal failure

PS Modlinger, CS Wilcox, S Aslam - Seminars in nephrology, 2004 - Elsevier
Cellular injury or organ dysfunction from oxidative stress occurs when reactive oxygen
species (ROS) accumulate in excess of the host defense mechanisms. The deleterious effect …

Effect of chronic renal failure on nitric oxide metabolism

ND Vaziri - American Journal of Kidney Diseases, 2001 - Elsevier
Chronic renal failure (CRF) is associated with hypertension, endothelial dysfunction, and a
strong propensity for arteriosclerotic cardiovascular disease. Nitric oxide (NO) is an …

Nitric oxide production is low in end-stage renal disease patients on peritoneal dialysis

RJ Schmidt, S Yokota, TS Tracy… - American Journal of …, 1999 - journals.physiology.org
To test the hypothesis that nitric oxide (NO) deficiency occurs in end-stage renal disease
(ESRD), NO oxidation products (NO2+ NO3= NOx) and cGMP were measured in blood …

Nitric oxide in renal health and disease

BC Kone - American journal of kidney diseases, 1997 - Elsevier
Nitrix oxide (NO) is a labile radical gas that is widely acclaimed as one of the most important
molecules in biology. Through covalent modifications of target proteins and redox reactions …