SARS-CoV-2 spike E484K mutation reduces antibody neutralisation

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - The Lancet …, 2021 - thelancet.com
It is concerning that emerging variants of SARS-CoV-2 can evade neutralising antibodies
induced by previous infection or vaccination through mutations in the spike protein …

[HTML][HTML] The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - MedRxiv, 2021 - ncbi.nlm.nih.gov
One year in the coronavirus disease 2019 (COVID-19) pandemic, the first vaccines are
being rolled out under emergency use authorizations. It is of great concern that newly …

Antibody neutralisation of emerging SARS-CoV-2 subvariants: EG. 5.1 and XBC. 1.6

Q Wang, Y Guo, RM Zhang, J Ho, H Mohri… - The Lancet Infectious …, 2023 - thelancet.com
Although WHO has declared an end to the emergency phase of the COVID-19 pandemic,
SARS-CoV-2 has continued to spread and evolve, giving rise to new variants. 1 These new …

WHO international standard for SARS-CoV-2 antibodies to determine markers of protection

F Zhu, T Althaus, CW Tan, A Costantini, WN Chia… - The Lancet …, 2022 - thelancet.com
Several studies have shown that neutralising antibody level is a good biomarker for the
correlate of protection against SARS-CoV-2 infection. 1–3 However, results from these …

Neutralisation of ZF2001-elicited antisera to SARS-CoV-2 variants

X Zhao, A Zheng, D Li, R Zhang, H Sun, Q Wang… - The Lancet …, 2021 - thelancet.com
SARS-CoV-2 variants, particularly the recently emerged delta (B. 1.617. 2) variant, have
caused another wave of infection worldwide. 1, 2 Whether these variants are sensitive to the …

Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …

Neutralisation of SARS-CoV-2 lineage P. 1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an …

WM Souza, MR Amorim, R Sesti-Costa… - The Lancet …, 2021 - thelancet.com
Background Mutations accrued by SARS-CoV-2 lineage P. 1—first detected in Brazil in early
January, 2021—include amino acid changes in the receptor-binding domain of the viral …

Antigenicity and receptor affinity of SARS-CoV-2 BA. 2.86 spike

Q Wang, Y Guo, L Liu, LT Schwanz, Z Li, MS Nair, J Ho… - Nature, 2023 - nature.com
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.
2.86, has emerged and spread to numerous countries worldwide, raising alarm because its …

Neutralisation sensitivity of SARS-CoV-2 omicron subvariants to therapeutic monoclonal antibodies

D Yamasoba, Y Kosugi, I Kimura, S Fujita… - The Lancet Infectious …, 2022 - thelancet.com
2 Kimura I, Kosugi Y, Wu J, et al. The SARS-CoV-2 lambda variant exhibits enhanced
infectivity and immune resistance. Cell Rep 2022; 38: 110218. 3 Bruel T, Hadjadj J, Maes P …

[HTML][HTML] Infection-and vaccine-induced antibody binding and neutralization of the B. 1.351 SARS-CoV-2 variant

VV Edara, C Norwood, K Floyd, L Lai… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants with mutations in the spike protein is raising
concerns about the efficacy of infection-or vaccine-induced antibodies. We compared …