Intravitreal administration of erythropoietin and preservation of retinal ganglion cells in an experimental rat model of glaucoma

JC Tsai, L Wu, B Worgul, M Forbes, J Cao - Current Eye Research, 2005 - Taylor & Francis
Purpose: The aim of this pilot study was to evaluate the potential neuroprotective effect of an
intravitreal injection of erythropoietin (EPO) on retinal ganglion cell (RGC) preservation in an …

Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice

L Zhong, J Bradley, W Schubert… - … & visual science, 2007 - iovs.arvojournals.org
purpose. Retinal ganglion cell (RGC) loss occurs in response to increased intraocular
pressure (IOP) and/or retinal ischemia in glaucoma and leads to impairment of vision. This …

[HTML][HTML] Functional and structural effects of erythropoietin subconjunctival administration in glaucomatous animals

AP Resende, SG Rosolen, T Nunes, B São Braz… - Biomedicine …, 2019 - karger.com
Purpose: The present study aimed to assess functional and structural benefits of
erythropoietin (EPO) when administered subconjunctivally in the retina of glaucomatous rats …

Erythropoietin is increased in aqueous humor of glaucomatous eyes

ZY Wang, KK Zhao, PQ Zhao - Current eye research, 2010 - Taylor & Francis
Purpose: To determine the aqueous concentration of erythropoietin (EPO) in patients with
and without glaucoma. Methods: Prospective, comparative control study. Concentrations of …

Erythropoietin with retrobulbar administration protects retinal ganglion cells from acute elevated intraocular pressure in rats

Y Zhong, X Liu, Y Cheng, Y Min - Journal of ocular pharmacology …, 2008 - liebertpub.com
Objective: The aim of this study was to clarify whether erythropoietin (EPO) with a retrobulbar
administration could protect retinal ganglion cells (RGCs) from acute elevated intraocular …

Aqueous humor erythropoietin levels in patients with primary open-angle glaucoma

T Cumurcu, Y Bulut, HD Demir… - Journal of …, 2007 - journals.lww.com
Purpose To evaluate the levels of erythropoietin (EPO) in the aqueous humor in eyes with
primary open-angle glaucoma (POAG) and without glaucoma. Methods Levels of EPO were …

[HTML][HTML] Erythropoietin levels in aqueous humor of patients with glaucoma

N Nassiri, N Nassiri, M Majdi, HZ Mehrjardi… - Molecular …, 2012 - ncbi.nlm.nih.gov
Purpose To compare the aqueous concentration of erythropoietin (EPO) in eyes with primary
open-angle (POAG), pseudoexfoliative (PXFG), and neovascular (NVG) glaucoma with age …

Erythropoietin: a candidate neuroprotective agent in the treatment of glaucoma

JC Tsai, BJ Song, L Wu, M Forbes - Journal of Glaucoma, 2007 - journals.lww.com
Glaucoma is a progressive optic neuropathy that is the leading cause of irreversible
blindness in the world. Although methods to lower intraocular pressure are the mainstay of …

[HTML][HTML] Erythropoietin and VEGF promote neural outgrowth from retinal explants in postnatal rats

S Böcker-Meffert, P Rosenstiel, C Röhl… - … & visual science, 2002 - arvojournals.org
purpose. Recent studies have reported neuroprotective effects of erythropoietin (EPO) and
vascular endothelial growth factor (VEGF). The purpose of the present study was to clarify …

Up-regulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension

QL Fu, W Wu, H Wang, X Li, VWH Lee… - Cellular and molecular …, 2008 - Springer
Aims Recent studies have showed that erythropoietin (EPO) is a neuroprotectant for central
nerve system neurons in addition to being a hematopoietic cytokine in response to hypoxia …